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- Title
Case report: A rare case of malignant solitary fibrous tumor in an adult with an epithelioid pattern in the occipital region.
- Authors
Ke Huang; Wen-wen Liu; Xiu-wen Chen; Yin-hua Hao; Sen-yuan Luo; Ling-ling Yuan; Yu-gang Huang; Xian-bin Tang
- Abstract
We illustrated a rare case of malignant solitary fibrous tumor (MSFT) with epithelioid morphology in the occipital region of a 59-year-old female, in which a rare NAB2ex7-STAT6 exon15/16 double fusion subtype was detected by the Next-generation sequencing (NGS) and STAT6 immunohistochemistry (IHC) was diffusely and strongly positively expressed, without recurrence after 20 months of postoperative follow-up. The morphological and molecular genetic aspects and the differential diagnosis are described, and the relevant literature was assessed in order to broaden our understanding and diagnostic capability of this malignancy
- Subjects
NUCLEOTIDE sequencing; STAT proteins; DIFFERENTIAL diagnosis; IMMUNOHISTOCHEMISTRY; ADULTS
- Publication
Frontiers in Oncology, 2024, p1
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2024.1339582