We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters.
- Authors
Lima, Fabio; Sharma, Upendra K.; Grunenberg, Lars; Saha, Debasmita; Johannsen, Sandra; Sedelmeier, Joerg; Van der Eycken, Erik V.; Ley, Steven V.
- Abstract
We report herein the use of a dual catalytic system comprising a Lewis base catalyst such as quinuclidin-3-ol or 4-dimethylaminopyridine and a photoredox catalyst to generate carbon radicals from either boronic acids or esters. This system enabled a wide range of alkyl boronic esters and aryl or alkyl boronic acids to react with electron-deficient olefins via radical addition to efficiently form C−C coupled products in a redox-neutral fashion. The Lewis base catalyst was shown to form a redox-active complex with either the boronic esters or the trimeric form of the boronic acids (boroxines) in solution.
- Subjects
ESTERS; CATALYSIS; LEWIS bases; QUINUCLIDINES; BORONIC acids; PHYSICAL &; theoretical chemistry
- Publication
Angewandte Chemie, 2017, Vol 129, Issue 47, p15332
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201709690