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- Title
Primary pediatric cardiac malignancies: the SEER experience.
- Authors
Davis, James; Allan, Bassan; Perez, Eduardo; Neville, Holly; Sola, Juan
- Abstract
Purpose: Pediatric cardiac malignancies are exceedingly rare. We sought to examine demographics, presentation, and outcomes for this pathology. Methods: The SEER registry from 1973 to 2008 was queried for all patients <20 years of age with cardiac malignancies. Results: A total of 25 pediatric patients were identified with primary cardiac malignancies, with age-adjusted incidence of 0.00686 per 100,000 United States population. Median age at diagnosis was 10 years. The majority of patients were adolescent ( n = 13, 52 %), Caucasian ( n = 17, 68 %) and males ( n = 14, 56 %). The most common histology was soft tissue sarcoma ( n = 10, 40%), followed by non-Hodgkin lymphoma and teratoma (both n = 3, 12 %). Six patients presented with distant disease. More than half of patients ( n = 16, 64 %) underwent surgical resection, while four patients (16 %) underwent radiation. The mean survival time for the cohort was 47 ± 67 months, with 14 (56 %) patients dying over the study period. Lymphomas had significantly longer survival than other malignancies (108 ± 66 vs. 36 ± 66, p = 0.03), while lack of surgical treatment was associated with worse survival ( p = 0.016). Conclusions: Primary malignant cardiac tumors are exceedingly rare in pediatric patients. They are most commonly soft tissue sarcomas and lymphomas demonstrated longer survival.
- Subjects
UNITED States; CHILDHOOD cancer; HEART cancer; SURGICAL excision; PEDIATRIC surgery; SOFT tissue tumors; LYMPHOMAS
- Publication
Pediatric Surgery International, 2013, Vol 29, Issue 5, p425
- ISSN
0179-0358
- Publication type
Article
- DOI
10.1007/s00383-013-3261-4