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- Title
Impact of iterative reconstruction on CT coronary calcium quantification.
- Authors
Kurata, Akira; Dharampal, Anoeshka; Dedic, Admir; de Feyter, Pim J; Krestin, Gabriel P; Dijkshoorn, Marcel L; Nieman, Koen
- Abstract
<bold>Objectives: </bold>We evaluated the influence of sinogram-affirmed iterative reconstruction (SAFIRE) on the coronary artery calcium (CAC) score by computed tomography (CT).<bold>Materials and Methods: </bold>Seventy patients underwent CAC imaging by 128-slice dual-source CT. CAC volume, mass and Agatston score were calculated from images reconstructed by filtered back projection (FBP) without and with incremental degrees of the SAFIRE algorithm (10-50 %). We used the repeated measuring test and the Steel-Dwass test for multiple comparisons of values and the difference ratio among different SAFIRE groups using the FBP as reference.<bold>Results: </bold>The median Agatston score (range) decreased with incremental SAFIRE degrees: 163 (0.1 - 3,393.3), 158.4 (0.3 - 3,079.3), 137.7 (0.1 - 2,978.0), 120.6 (0 - 2,783.6), 102.6 (0 - 2,468.4) and 84.1 (0 - 2,186.9) for 0 % (FBP), 10 %, 20 %, 30 %, 40 % and 50 % SAFIRE, respectively (P < 0.05). In comparison with FBP, CAC volume (from 8.1 % to 47.7 %), CAC mass (from 5.3 % to 44.7 %) and CAC Agatston score (from 7.3 % to 48.4 %) all decreased with increasing SAFIRE from 10 % to 50 %, respectively (P < 0.05). High-grade SAFIRE resulted in the disappearance of detectable calcium in three cases with low calcium burden.<bold>Conclusion: </bold>SAFIRE noise reduction techniques significantly affected the CAC, which potentially alters perceived cardiovascular risk.
- Publication
European Radiology, 2013, Vol 23, Issue 12, p3246
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-013-3022-8