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- Title
Brief report. Polymorphisms in angiotensin-converting enzyme gene and severity of renal disease in Henoch-Schoenlein patients.
- Authors
Amoroso, A; Danek, G; Vatta, S; Crovella, S; Berrino, M; Guarrera, S; Fasano, ME; Mazzola, G; Amore, A; Gianoglio, B; Peruzzi, L; Coppo, R
- Abstract
Background.The influence of angiotensin converting enzyme (ACE) gene polymorphism on the progression of primary IgA nephropathy (pIgAN) is still debated. Even though the allele frequency was reported to be similar to controls, in some studies D/D patients had a faster decline of renal function and need of dialysis. Since Henoch-Schoenlein purpura (HSP) nephritis is considered a systemic vasculitis with renal lesions indistinguishable from pIgAN, we investigated the effect of the ACE polymorphism on presentation and progression of HSP IgAN.
- Publication
Nephrology Dialysis Transplantation, 1998, Vol 13, Issue 12, p3184
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/13.12.3184