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The Sexual Dimorphism in Cerebrospinal Fluid Protein Content Does Not Affect Intrathecal IgG Synthesis in Multiple Sclerosis.
Published in:
Journal of Personalized Medicine, 2022, v. 12, n. 6, p. 977, doi. 10.3390/jpm12060977
By:
- Castellazzi, Massimiliano;
- Ferri, Caterina;
- Tecilla, Ginevra;
- Huss, André;
- Crociani, Paola;
- Desina, Gaetano;
- Barbella, Gianvito;
- Piola, Alice;
- Permunian, Samantha;
- Senel, Makbule;
- Leone, Maurizio;
- Tumani, Hayrettin;
- Pugliatti, Maura
Publication type:
Article
A Score Based on NfL and Glial Markers May Differentiate Between Relapsing–Remitting and Progressive MS Course.
Published in:
Frontiers in Neurology, 2020, v. 11, p. 1, doi. 10.3389/fneur.2020.00608
By:
- Huss, André;
- Otto, Markus;
- Senel, Makbule;
- Ludolph, Albert C.;
- Abdelhak, Ahmed;
- Tumani, Hayrettin
Publication type:
Article
Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assays.
Published in:
Clinical Chemistry & Laboratory Medicine, 2024, v. 62, n. 8, p. 1591, doi. 10.1515/cclm-2023-1256
By:
- Fazeli, Badrieh;
- Gómez de San José, Nerea;
- Jesse, Sarah;
- Senel, Makbule;
- Oeckl, Patrick;
- Erhart, Deborah K.;
- Ludolph, Albert C.;
- Otto, Markus;
- Halbgebauer, Steffen;
- Tumani, Hayrettin
Publication type:
Article
Free light chains in the cerebrospinal fluid. Comparison of different methods to determine intrathecal synthesis.
Published in:
Clinical Chemistry & Laboratory Medicine, 2019, v. 57, n. 10, p. 1574, doi. 10.1515/cclm-2018-1300
By:
- Hegen, Harald;
- Walde, Janette;
- Milosavljevic, Dejan;
- Aboulenein-Djamshidian, Fahmy;
- Senel, Makbule;
- Tumani, Hayrettin;
- Deisenhammer, Florian;
- Presslauer, Stefan
Publication type:
Article
Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis.
Published in:
Annals of Clinical & Translational Neurology, 2024, v. 11, n. 2, p. 477, doi. 10.1002/acn3.51969
By:
- Abdelhak, Ahmed;
- Antweiler, Kai;
- Kowarik, Markus C.;
- Senel, Makbule;
- Havla, Joachim;
- Zettl, Uwe K.;
- Kleiter, Ingo;
- Skripuletz, Thomas;
- Haarmann, Axel;
- Stahmann, Alexander;
- Huss, Andre;
- Gingele, Stefan;
- Krumbholz, Markus;
- Benkert, Pascal;
- Kuhle, Jens;
- Friede, Tim;
- Ludolph, Albert C.;
- Ziemann, Ulf;
- Kümpfel, Tania;
- Tumani, Hayrettin
Publication type:
Article
Differentiation of viral and autoimmune central nervous system inflammation by kynurenine pathway.
Published in:
Annals of Clinical & Translational Neurology, 2021, v. 8, n. 12, p. 2228, doi. 10.1002/acn3.51383
By:
- Luo, Yi;
- Möhn, Nora;
- Skripuletz, Thomas;
- Senel, Makbule;
- Tumani, Hayrettin;
- Peßler, Frank;
- Sühs, Kurt‐Wolfram;
- Stangel, Martin
Publication type:
Article
Tick-Borne Encephalitis: A Differential Pattern of Intrathecal Humoral Immune Response and Inflammatory Cell Composition Compared with Other Viral CNS Infections.
Published in:
Cells (2073-4409), 2020, v. 9, n. 10, p. 2169, doi. 10.3390/cells9102169
By:
- Senel, Makbule;
- Rapp, Daniel;
- Mayer, Benjamin;
- Jesse, Sarah;
- Süssmuth, Sigurd D.;
- Otto, Markus;
- Lewerenz, Jan;
- Tumani, Hayrettin
Publication type:
Article
Cognition in patients with neuromyelitis optica spectrum disorders: A prospective multicentre study of 217 patients (CogniNMO-Study).
Published in:
Multiple Sclerosis Journal, 2023, v. 29, n. 7, p. 819, doi. 10.1177/13524585231151212
By:
- Hümmert, Martin W;
- Stern, Carlotta;
- Paul, Friedemann;
- Duchow, Ankelien;
- Bellmann-Strobl, Judith;
- Ayzenberg, Ilya;
- Schwake, Carolin;
- Kleiter, Ingo;
- Hellwig, Kerstin;
- Jarius, Sven;
- Wildemann, Brigitte;
- Senel, Makbule;
- Berthele, Achim;
- Giglhuber, Katrin;
- Luessi, Felix;
- Grothe, Matthias;
- Klotz, Luisa;
- Schülke, Rasmus;
- Gingele, Stefan;
- Faiss, Jürgen H
Publication type:
Article
Validation of kappa free light chains as a diagnostic biomarker in multiple sclerosis and clinically isolated syndrome: A multicenter study.
Published in:
Multiple Sclerosis Journal, 2016, v. 22, n. 4, p. 502, doi. 10.1177/1352458515594044
By:
- Presslauer, Stefan;
- Milosavljevic, Dejan;
- Huebl, Wolfgang;
- Aboulenein-Djamshidian, Fahmy;
- Krugluger, Walter;
- Deisenhammer, Florian;
- Senel, Makbule;
- Tumani, Hayrettin;
- Hegen, Harald
Publication type:
Article
Intrathecal immunoglobulin M production: A promising high-risk marker in clinically isolated syndrome patients.
Published in:
2018
By:
- Huss, André;
- Abdelhak, Ahmed;
- Halbgebauer, Steffen;
- Mayer, Benjamin;
- Senel, Makbule;
- Otto, Markus;
- Tumani, Hayrettin
Publication type:
journal article
Longitudinal Serum Neurofilament Levels of Multiple Sclerosis Patients Before and After Treatment with First-Line Immunomodulatory Therapies.
Published in:
Biomedicines, 2020, v. 8, n. 9, p. 312, doi. 10.3390/biomedicines8090312
By:
- Huss, André;
- Senel, Makbule;
- Abdelhak, Ahmed;
- Mayer, Benjamin;
- Kassubek, Jan;
- Ludolph, Albert C.;
- Otto, Markus;
- Tumani, Hayrettin
Publication type:
Article
Stress cardiomyopathy associated with the first manifestation of multiple sclerosis: a case report.
Published in:
2020
By:
- Rapp, Daniel;
- Keßler, Mirjam;
- Pinkhardt, Elmar;
- Otto, Markus;
- Tumani, Hayrettin;
- Senel, Makbule
Publication type:
journal article
Rheumatoid factor IgM autoantibodies control IgG homeostasis.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1016263
By:
- Nicolò, Antonella;
- Amendt, Timm;
- Ayoubi, Omal El;
- Young, Marc;
- Finzel, Stephanie;
- Senel, Makbule;
- Voll, Reinhard E.;
- Jumaa, Hassan
Publication type:
Article
Safety and Tolerability of Plasma Exchange and Immunoadsorption in Neuroinflammatory Diseases.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 9, p. 2874, doi. 10.3390/jcm9092874
By:
- Dorst, Johannes;
- Fillies, Frank;
- Dreyhaupt, Jens;
- Senel, Makbule;
- Tumani, Hayrettin
Publication type:
Article
Immunoadsorption and Plasma Exchange in Seropositive and Seronegative Immune-Mediated Neuropathies.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 7, p. 2025, doi. 10.3390/jcm9072025
By:
- Davies, Alexander J.;
- Fehmi, Janev;
- Senel, Makbule;
- Tumani, Hayrettin;
- Dorst, Johannes;
- Rinaldi, Simon
Publication type:
Article
Cerebrospinal Fluid Immunoglobulin Kappa Light Chain in Clinically Isolated Syndrome and Multiple Sclerosis.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0088680
By:
- Senel, Makbule;
- Tumani, Hayrettin;
- Lauda, Florian;
- Presslauer, Stefan;
- Mojib-Yezdani, Rehaneh;
- Otto, Markus;
- Brettschneider, Johannes
Publication type:
Article
The Chemokine CXCL13 Is a Prognostic Marker in Clinically Isolated Syndrome (CIS).
Published in:
PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0011986
By:
- Brettschneider, Johannes;
- Czerwoniak, Anne;
- Senel, Makbule;
- Lubin Fang;
- Kassubek, Jan;
- Pinkhardt, Elmar;
- Lauda, Florian;
- Kapfer, Tamara;
- Jesse, Sarah;
- Lehmensiek, Vera;
- Ludolph, Albert C.;
- Otto, Markus;
- Tumani, Hayrettin
Publication type:
Article
Diagnostic biomarkers in tear fluid: from sampling to preanalytical processing.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89514-8
By:
- Bachhuber, Franziska;
- Huss, André;
- Senel, Makbule;
- Tumani, Hayrettin
Publication type:
Article
Serum neurofilament light chain and glial fibrillary acidic protein for predicting response to apheresis in steroid‐refractory multiple sclerosis relapses.
Published in:
European Journal of Neurology, 2024, v. 31, n. 8, p. 1, doi. 10.1111/ene.16323
By:
- Vardakas, Ioannis;
- Dorst, Johannes;
- Huss, André;
- Mayer, Benjamin;
- Fangerau, Tanja;
- Taranu, Daniela;
- Tumani, Hayrettin;
- Senel, Makbule
Publication type:
Article
Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation.
Published in:
Brain: A Journal of Neurology, 2014, v. 137, n. 10, p. 2703, doi. 10.1093/brain/awu205
By:
- Beltrán, Eduardo;
- Obermeier, Birgit;
- Moser, Markus;
- Coret, Francisco;
- Simó-Castelló, María;
- Boscá, Isabel;
- Pérez-Miralles, Francisco;
- Villar, Luisa M.;
- Senel, Makbule;
- Tumani, Hayrettin;
- Hohlfeld, Reinhard;
- Casanova, Bonaventura;
- Dornmair, Klaus
Publication type:
Article
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
Published in:
Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-021-02339-0
By:
- Jarius, Sven;
- Pache, Florence;
- Körtvelyessy, Peter;
- Jelčić, Ilijas;
- Stettner, Mark;
- Franciotta, Diego;
- Keller, Emanuela;
- Neumann, Bernhard;
- Ringelstein, Marius;
- Senel, Makbule;
- Regeniter, Axel;
- Kalantzis, Rea;
- Willms, Jan F.;
- Berthele, Achim;
- Busch, Markus;
- Capobianco, Marco;
- Eisele, Amanda;
- Reichen, Ina;
- Dersch, Rick;
- Rauer, Sebastian
Publication type:
Article
Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients.
Published in:
Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-021-02339-0
By:
- Jarius, Sven;
- Pache, Florence;
- Körtvelyessy, Peter;
- Jelčić, Ilijas;
- Stettner, Mark;
- Franciotta, Diego;
- Keller, Emanuela;
- Neumann, Bernhard;
- Ringelstein, Marius;
- Senel, Makbule;
- Regeniter, Axel;
- Kalantzis, Rea;
- Willms, Jan F.;
- Berthele, Achim;
- Busch, Markus;
- Capobianco, Marco;
- Eisele, Amanda;
- Reichen, Ina;
- Dersch, Rick;
- Rauer, Sebastian
Publication type:
Article
Correction to: Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management.
Published in:
2024
By:
- Kümpfel, Tania;
- Giglhuber, Katrin;
- Aktas, Orhan;
- Ayzenberg, Ilya;
- Bellmann-Strobl, Judith;
- Häußler, Vivien;
- Havla, Joachim;
- Hellwig, Kerstin;
- Hümmert, Martin W.;
- Jarius, Sven;
- Kleiter, Ingo;
- Klotz, Luisa;
- Krumbholz, Markus;
- Paul, Friedemann;
- Ringelstein, Marius;
- Ruprecht, Klemens;
- Senel, Makbule;
- Stellmann, Jan-Patrick;
- Bergh, Florian Then;
- Trebst, Corinna
Publication type:
Correction Notice
Myelitis as a side effect of tofersen therapy in SOD1-associated ALS.
Published in:
Journal of Neurology, 2024, v. 271, n. 4, p. 2114, doi. 10.1007/s00415-023-12130-1
By:
- Reilich, Peter;
- Schöberl, Florian;
- Hiebeler, Miriam;
- Tonon, Matthias;
- Ludolph, Albert C.;
- Senel, Makbule
Publication type:
Article
Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management.
Published in:
Journal of Neurology, 2024, v. 271, n. 1, p. 141, doi. 10.1007/s00415-023-11910-z
By:
- Kümpfel, Tania;
- Giglhuber, Katrin;
- Aktas, Orhan;
- Ayzenberg, Ilya;
- Bellmann-Strobl, Judith;
- Häußler, Vivien;
- Havla, Joachim;
- Hellwig, Kerstin;
- Hümmert, Martin W.;
- Jarius, Sven;
- Kleiter, Ingo;
- Klotz, Luisa;
- Krumbholz, Markus;
- Paul, Friedemann;
- Ringelstein, Marius;
- Ruprecht, Klemens;
- Senel, Makbule;
- Stellmann, Jan-Patrick;
- Bergh, Florian Then;
- Trebst, Corinna
Publication type:
Article
Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis.
Published in:
Journal of Neurology, 2023, v. 270, n. 7, p. 3341, doi. 10.1007/s00415-023-11634-0
By:
- Jarius, Sven;
- Aktas, Orhan;
- Ayzenberg, Ilya;
- Bellmann-Strobl, Judith;
- Berthele, Achim;
- Giglhuber, Katrin;
- Häußler, Vivien;
- Havla, Joachim;
- Hellwig, Kerstin;
- Hümmert, Martin W.;
- Kleiter, Ingo;
- Klotz, Luisa;
- Krumbholz, Markus;
- Kümpfel, Tania;
- Paul, Friedemann;
- Ringelstein, Marius;
- Ruprecht, Klemens;
- Senel, Makbule;
- Stellmann, Jan-Patrick;
- Bergh, Florian Then
Publication type:
Article
Varicella zoster virus-induced neurological disease after COVID-19 vaccination: a retrospective monocentric study.
Published in:
Journal of Neurology, 2022, v. 269, n. 4, p. 1751, doi. 10.1007/s00415-021-10849-3
By:
- Abu-Rumeileh, Samir;
- Mayer, Benjamin;
- Still, Veronika;
- Tumani, Hayrettin;
- Otto, Markus;
- Senel, Makbule
Publication type:
Article
Short-term and long-term effects of immunoadsorption in refractory chronic inflammatory demyelinating polyneuropathy: a prospective study in 17 patients.
Published in:
Journal of Neurology, 2018, v. 265, n. 12, p. 2906, doi. 10.1007/s00415-018-9082-6
By:
- Dorst, Johannes;
- Ludolph, Albert C.;
- Senel, Makbule;
- Tumani, Hayrettin
Publication type:
Article
Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing–remitting multiple sclerosis, the ProVal-MS study.
Published in:
Neurological Research & Practice, 2024, v. 6, n. 1, p. 1, doi. 10.1186/s42466-024-00310-x
By:
- Bayas, Antonios;
- Mansmann, Ulrich;
- Ön, Begum Irmak;
- Hoffmann, Verena S.;
- Berthele, Achim;
- Mühlau, Mark;
- Kowarik, Markus C.;
- Krumbholz, Markus;
- Senel, Makbule;
- Steuerwald, Verena;
- Naumann, Markus;
- Hartberger, Julia;
- Kerschensteiner, Martin;
- Oswald, Eva;
- Ruschil, Christoph;
- Ziemann, Ulf;
- Tumani, Hayrettin;
- Vardakas, Ioannis;
- Albashiti, Fady;
- Kramer, Frank
Publication type:
Article
Clinical associations and characteristics of the polyspecific intrathecal immune response in elderly patients with non-multiple sclerosis chronic autoimmune-inflammatory neurological diseases - a retrospective cross-sectional study.
Published in:
Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1193015
By:
- Brauchle, Felix;
- Rapp, Daniel;
- Senel, Makbule;
- Huss, André;
- Dreyhaupt, Jens;
- Klose, Veronika;
- Süße, Marie;
- Stürner, Klarissa Hanja;
- Leypoldt, Frank;
- Tumani, Hayrettin;
- Lewerenz, Jan
Publication type:
Article
Patterns of Th1/Th2 Cytokines Predict Clinical Response in Multiple Sclerosis Patients Treated with Glatiramer Acetate.
Published in:
European Neurology, 2011, v. 65, n. 3, p. 164, doi. 10.1159/000324035
By:
- Tumani, Hayrettin;
- Kassubek, Jan;
- Hijazi, Mohammed;
- Lehmensiek, Vera;
- Unrath, Alexander;
- Süssmuth, Sigurd;
- Lauda, Florian;
- Kapfer, Tamara;
- Fang, Lubin;
- Senel, Makbule;
- Brettschneider, Johannes
Publication type:
Article
Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis.
Published in:
Therapeutic Advances in Neurological Disorders, 2023, p. 1, doi. 10.1177/17562864231161892
By:
- Hapfelmeier, Alexander;
- On, Begum Irmak;
- Mühlau, Mark;
- Kirschke, Jan S.;
- Berthele, Achim;
- Gasperi, Christiane;
- Mansmann, Ulrich;
- Wuschek, Alexander;
- Bussas, Matthias;
- Boeker, Martin;
- Bayas, Antonios;
- Senel, Makbule;
- Havla, Joachim;
- Kowarik, Markus C.;
- Kuhn, Klaus;
- Gatz, Ingrid;
- Spengler, Helmut;
- Wiestler, Benedikt;
- Grundl, Lioba;
- Sepp, Dominik
Publication type:
Article
Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis.
Published in:
Therapeutic Advances in Neurological Disorders, 2023, v. 16, p. 1, doi. 10.1177/17562864231161892
By:
- Hapfelmeier, Alexander;
- On, Begum Irmak;
- Mühlau, Mark;
- Kirschke, Jan S.;
- Berthele, Achim;
- Gasperi, Christiane;
- Mansmann, Ulrich;
- Wuschek, Alexander;
- Bussas, Matthias;
- Boeker, Martin;
- Bayas, Antonios;
- Senel, Makbule;
- Havla, Joachim;
- Kowarik, Markus C.;
- Kuhn, Klaus;
- Gatz, Ingrid;
- Spengler, Helmut;
- Wiestler, Benedikt;
- Grundl, Lioba;
- Sepp, Dominik
Publication type:
Article
Phelan McDermid Syndrome: Multiple Sclerosis as a Rare but Treatable Cause for Regression—A Case Report.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2311, doi. 10.3390/ijms22052311
By:
- Jesse, Sarah;
- Delling, Jan Philipp;
- Schön, Michael;
- Boeckers, Tobias M;
- Ludolph, Albert;
- Senel, Makbule;
- Comi, Cristoforo
Publication type:
Article
CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00641
By:
- Senel, Makbule;
- Mojib-Yezdani, Fatemeh;
- Braisch, Ulrike;
- Bachhuber, Franziska;
- Lewerenz, Jan;
- Ludolph, Albert C.;
- Otto, Markus;
- Tumani, Hayrettin
Publication type:
Article
CXCL13 in Cerebrospinal Fluid: Clinical Value in a Large Cross-Sectional Study.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 425, doi. 10.3390/ijms25010425
By:
- Erhart, Deborah Katharina;
- Klose, Veronika;
- Schäper, Tatjana;
- Tumani, Hayrettin;
- Senel, Makbule
Publication type:
Article

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