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- Title
基于瞬发伽马谱学的元素重建算法.
- Authors
汪金龙; 吴晓光; 杨立旺; 赵子豪; 郑云; 李聪博; 李天晓; 郑敏
- Abstract
Prompt gamma ray in proton therapy is the product of nuclear reaction between proton and target. The characteristic energies and intensities of prompt gamma lines can be used to determine the types of elements and their amounts in the target. In several previous experiments, it has been demonstrated that no matter how complex the reaction cross-section is, once the energy of the incident proton and the irradiated element are determined, there is a definite linear relationship between the element concentration and the number of gamma-ray photons. However, this linear relationship is difficult to apply to medical imaging and the nonlinear behavior of hydrogen has not been investigated to date・ This linear relationship is extended to mixed elemental materials including nonlinear case such as hydrogen, and a universal mathematical form, which is referred to as the prompt gamma spectroscopy retrieval algorithm (PGSRA), is developed. The basic assumption of the PGSRA is that the PGS of the sample material has a relationship with the molar gamma lines of the elements. For carbon and oxygen, this relationship is linear, while for hydrogen, it is nonlinear・ As the 2. 23 MeV gamma line originates from neutron absorption radiation, the behavior of hydrogen is carefully investigated. The linear and nonlinear relationships are verified using Monte Carlo simulations with different combinations of carbon, oxygen, and hydrogen, such as PMMA, pentanediol and ethanedioL The relative errors of carbon and oxygen in all samples are less than 4% for all the sample materials. The relative errors of hydrogen, based on its nonlinear behavior, is approximately 10%. In addition, the relative errors of the sample density are less than 3・ 5% for all the sample materials. The PGSRA developed in this work could be the first bridge between PGS and medical imaging.
- Publication
Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue, 2024, Vol 14, Issue 6, p842
- ISSN
2095-1035
- Publication type
Article
- DOI
10.3969/j.issn.2095-1035.2024.06.017