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- Title
Impaired Exercise Capacity and Mortality Risk in Adults with Congenital Heart Disease.
- Authors
Banik, Rahul; Geelani, Mohammad Abid; Singh, Harpreet
- Abstract
Background: The prevalence of congenital heart disease (CHD) among adults has increased due to improved medical care. Impaired exercise capacity is a significant concern in this population, with potential implications for mortality risk. Methods: A retrospective cohort study involving 40 adults with CHD was conducted over one year. Exercise capacity parameters (peak VO2, exercise duration, peak heart rate) were assessed using cardiopulmonary exercise testing. Mortality outcomes were recorded, and Cox proportional hazards regression and Kaplan-Meier survival analyses were performed. Results: Mean peak VO2 was 22.1 ± 3.8 ml/kg/min, exercise duration was 8.5 ± 2.1 min, and peak heart rate was 156 ± 12 bpm. During the study, 15% (n=6) of participants experienced mortality. Associations between exercise capacity parameters and mortality risk were observed, but did not reach statistical significance (peak VO2: HR = 0.81, p = 0.065; exercise duration: HR = 0.95, p = 0.487; peak heart rate: HR = 1.12, p = 0.188). Kaplan-Meier survival analysis showed a declining survival probability over 12 months (77%). Conclusion: This study highlights potential trends between impaired exercise capacity and mortality risk in adults with CHD. While associations were not statistically significant, the findings underscore the need for further research with larger samples and longer follow-up periods to comprehensively understand the complex relationship between exercise capacity and mortality outcomes in this population.
- Subjects
AEROBIC capacity; CONGENITAL heart disease; EXERCISE tests; HEART beat; ADULTS
- Publication
Indian Journal of Basic & Applied Medical Research, 2023, Vol 12, Issue 4, p11
- ISSN
2250-284X
- Publication type
Article
- DOI
10.36855/IJBAMR/2022/98215.6228