We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of an Amino Acid, Protein, and Carbohydrate Mixture on Net Muscle Protein Balance After Resistance Exercise.
- Authors
Børsheim, Elisabet; Aarsland, Asle; Wolfe, Robert R.
- Abstract
This study tests the hypotheses that (a) a mixture of whey protein, amino acids (AA), and carbohydrates (CHO) stimulates net muscle protein synthesis to a greater extent than isoenergetic CHO alone after resistance exercise; and (b) that the stimulatory effect of a protein, AA, and CHO mixture will last beyond the 1st hour after intake. Eight subjects participated in 2 trials. In one (PAAC), they ingested 77.4 g CHO, 17.5 g whey protein, and 4.9 g AA 1 hr after resistance exercise. In the other (CON), 100 g CHO was ingested instead. They received a primed constant infusion of L-[²H[sub5]]-phenylalanine, and samples from femoral artery and vein, and biopsies from vastus lateralis were obtained. The area under the curve for net uptake of phenylalanine into muscle above predrink value was 128 ± 42 mg ⋅ leg[sup-1] (PAAC) versus 32 ± 10 mg ⋅ leg[sup-1]) (CON) for the 3 hr after the drink (p = .04). The net protein balance response to the mixture consisted of two components, one rapid immediate response, and a smaller delayed response about 90 min after drink, whereas in CON only a small delayed response was seen. We conclude that after resistance exercise, a mixture of whey protein, AA, and CHO stimulated muscle protein synthesis to a greater extent than isoenergetic CHO alone. Further, compared to previously reported findings, the addition of protein to an AA + CHO mixture seems to extend the anabolic effect.
- Subjects
WHEY; AMINO acids; CARBOHYDRATES; MUSCLE proteins; PROTEIN synthesis; EXERCISE; PHENYLALANINE; BIOPSY; ISOMETRIC exercise
- Publication
International Journal of Sport Nutrition & Exercise Metabolism, 2004, Vol 14, Issue 3, p255
- ISSN
1526-484X
- Publication type
Article