We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
弹性成像定量分析联合硬环征在甲状腺良恶性结节鉴别诊断中 的应用价值分析
- Authors
牛艳; 周琦; 李娜; 钟娜; 吴琼; 刘慧; 刘慧平
- Abstract
Objective: To explore the diagnostic value of elastic quantitative analysis combined with hard ring sign for differentiating benign and malignant thyroid nodules. Methods: The clinical data of 121 cases of patients with thyroid nodules confirmed by operation or biopsy in our hospital from January 2018 to September 2018 were retrospectively analyzed. All the patients underwent elastography quantitative analysis and shear wave elastography (SWE) analysis. Quantitative analysis of elastography, SWE analysis and combined detection were performed. The results were golden standard (78 benign and 43 malignant), sensitivity, specificity, accuracy, positive predictive value and negative predictive value for the diagnosis of benign and malignant thyroid nodules. Quantitative analysis of elastography, SWE and ROC curves were drawn respectively, and the areas under ROC curves were compared. Results: (1) Elastic quantitative analysis of 87 benign nodules, 34 malignant, the sensitivity was 73.08%, the specificity was 30.23%, the positive predictive value was 65.51%, the negative predictive value was 38.24%; (2) SWE analysis of 76 benign nodules, 45 malignant nodules, the sensitivity was 64.10%, the specificity was 39.53%, the positive predictive value was 65.79%, the negative predictive value was 37.78%; (3) 73 benign nodules, 48 malignant nodules, the sensitivity was 89.74%, the specificity was 93.02%, the positive predictive value was 95.89%, the negative predictive value was 83.33%; (4) The sensitivity, specificity, positive predictive value and negative predictive value of combined detection were higher than those of single detection (P<0.05); (5) Quantitative analysis of elastography. The area under ROC curve was 0.843, 0.819 and 0.940, respectively. The accuracy of combined detection was higher than that of single method (P<0.05). SWE analysis of the modulus of elasticity of benign and malignant thyroid nodules Emean, Emin, Emax, Esd, Emean-p and Emean-m were significantly larger than the malignant nodules (P<0.05). Conclusions: Quantitative analysis of elastography combined with hard ring sign detection can significantly improve the sensitivity and specificity in the diagnosis of benign and malignant thyroid nodules, and it has high clinical value.
- Subjects
MODULUS of elasticity; RECEIVER operating characteristic curves; QUANTITATIVE chemical analysis; ELASTIC analysis (Engineering); WAVE analysis
- Publication
Progress in Modern Biomedicine, 2019, Vol 19, Issue 5, p894
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2019.05.022