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- Title
复方鳖甲软肝片联合阿德福韦酯对乙肝肝硬化患者肝功能和乙肝血清标志物水平的影响
- Authors
黄俊; 向徳森; 付晓; 陈瀑; 罗鹏; 邹麟
- Abstract
Objective: To investigate the effects of fufang biejia ruangan tablets combined with adefovir dipivoxil on the levels of hepatitis B serum markers in patients with hepatitis B liver cirrhosis. Methods: 60 patients with hepatitis B liver cirrhosis who were treated in our hospital were selected and randomly divided into the experiment group and the control group, with 30 cases in each group. The patients in the control group were treated with adefovirdipivoxil, and the patients in the experiment group were treated with Fufang biejia ruangan tablets on the basis of the control group. Then the serum levels of albumin (ALB), alanine aminotransferase (ALT), total bilirubin (TBIL) and the thrombin time (PT), incidence of adverse reactions, the HBeAg negative rate, HBV-DNA negative rate and HBeAg serum conversion rate of patients in the two groups were observed and compared after treatment. Results: Compared with before treatment, the serum levels of ALB in both groups were increased after the treatment, while the levels of ALT, TBIL and PT were decreased (P<0.05). Compared with the control group after the treatment, the serum level of ALB in the experiment group was higher, while the levels of ALT, TBIL and PT were lower (P<0.05); Compared with the control group, the incidence of adverse reactions and the HBeAg negative rate, HBV-DNA negative rate and HBeAg serum conversion rate of experiment group were lower (P<0.05). Conclusion: Fufang biejia ruangan tablets combine with Adefovir dipivoxil in the treatment of patients with hepatitis B liver cirrhosis had good clinical efficacy, which was worthy of clinical application.
- Publication
Progress in Modern Biomedicine, 2017, Vol 17, Issue 7, p1335
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2017.07.035