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- Title
Reference values for amino acids and acylcarnitines in peripheral blood in Quarter horses and American Miniature horses.
- Authors
Rodríguez‑Sánchez, Irám Pablo; Treviño‑Alvarado, Víctor Manuel; del Rosario Torres‑Sepúlveda, María; López‑Saldaña, Liliana Aracely; Ponce‑García, Gustavo; López‑Uriarte, Graciela Areli; del Consuelo Ruiz‑Herrera, María; Zamora‑Ávila, Diana Elisa; Villarreal‑Pérez, Jesús Zacarías; Dávalos‑Aranda, Guillermo; Martínez-de-Villarreal, Laura Elia
- Abstract
Background: Free amino acids and acylcarnitines circulating in the blood can be used for diagnosis for metabolic illness and imbalances. To date, the normal reference ranges of amino acids and acylcarnitines in horse peripheral blood have not been established. In this study, the concentrations of 12 amino acids and 26 acylcarnitines were determined by tandem mass spectrometry in complete blood from 100 healthy horses (50 Quarter horses (QH) [23 males and 27 females] and 50 American Miniature horses (AMH) [15 males and 35 females]) with no signs of metabolic disease. The means and standard deviations were determined and data statistically analyzed. Findings: Concentrations of short, medium, and long chain acylcarnitines were significantly higher in male AMH than in male QH. The concentrations of the amino acids alanine, arginine, glycine, proline (glycogenic), and leucine (ketogenic) were higher in the QH than in the AMH. Female AMH had higher concentrations of propionylcarnitine, leucine, proline, arginine, and ornithine than female QH. Conclusions: Normal reference ranges of amino acids and acylcarnitines were established for AMH and QH. Significant differences were found in concentration of these compounds between breeds and gender.
- Subjects
THERAPEUTIC use of amino acids; METABOLIC disorder diagnosis; HORSE health; MINIATURE horses; TANDEM mass spectrometry; DISEASES
- Publication
Acta Veterinaria Scandinavica, 2015, Vol 57, Issue 1, p1
- ISSN
0044-605X
- Publication type
Article
- DOI
10.1186/s13028-015-0144-9