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- Title
Assessing the Impact of Spraying an Enterococcus faecium- Based Probiotic on Day-Old Broiler Chicks at Hatch on the Incidence of Bacterial Chondronecrosis with Osteomyelitis Lameness Using a Staphylococcus Challenge Model.
- Authors
Do, Anh Dang Trieu; Anthney, Amanda; Alharbi, Khawla; Asnayanti, Andi; Meuter, Antoine; Alrubaye, Adnan Ali Khalaf
- Abstract
Simple Summary: Bacterial chondronecrosis with osteomyelitis-induced lameness presents a substantial challenge within the avian agricultural sector. The etiology involves pathogenic bacteria translocating from a compromised intestinal barrier into the bloodstream, subsequently colonizing microfractures present in the leg bones that are caused by rapid growth rate and heavy bird weight, resulting in damage and lameness. This study aims to assess whether spraying a non-pathogenic strain of Enterococcus faecium bacteria at two different concentrations on day-of-hatch chicks is effective in reducing lameness in broilers using a Staphylococcus challenge model. Results indicate that dosing day-old chicks with an effective probiotic reduced lameness incidence in a dose-dependent manner. Findings from this study contribute to the overall understanding of efficient and sustainable broiler production as a high-quality and affordable source of animal protein, while improving bird health and welfare at the same time. Bacterial chondronecrosis with osteomyelitis (BCO) lameness is a bone disease characterized by the translocation of bacteria from the gastrointestinal tract, which colonize microfractures in broiler leg bones caused by rapid animal growth rate and weight gain, resulting in lameness. As such, BCO lameness represents a significant challenge for the poultry industry. This study aims to evaluate the effect of spraying broiler chicks on d0 at hatch with an Enterococcus faecium probiotic on the incidence of BCO-induced lameness, utilizing a Staphylococcus aureus challenge model. There were four treatments: (1) negative control (no probiotic + no challenge, NC); (2) positive control (no probiotic + challenge, PC); (3) low dosage (4.0 × 108 CFU/chick + challenge, LOW); and (4) high dosage (2.0 × 109 CFU/chick + challenge, HIGH). On d5, groups two through four were challenged with Staphylococcus aureus through the drinking water at a concentration of 1.0 × 105 CFU/mL. Cumulative lameness incidence was determined through daily evaluations and necropsies conducted on lame birds starting from d22. Data were subjected to a binomial general regression analysis (significant p < 0.05). On d56, the PC group exhibited the highest cumulative lameness incidence (58.0%; p < 0.05), followed by LOW (36.0%), HIGH (28.7%), and NC groups (25.3%), respectively. These results suggest early probiotic application at day-of-hatch successfully reduced the incidence of lameness in challenged birds, thus contributing to understanding of efficient and sustainable broiler production.
- Subjects
PROBIOTICS; CHICKS; STAPHYLOCOCCUS; ENTEROCOCCUS; SUSTAINABILITY; PATHOGENIC bacteria
- Publication
Animals (2076-2615), 2024, Vol 14, Issue 9, p1369
- ISSN
2076-2615
- Publication type
Article
- DOI
10.3390/ani14091369