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- Title
Multiple Coronary Artery Thrombosis in 5,10-Methylenetetrahydrofolate Reductase Gene Mutation.
- Authors
Campanile, Alfonso; Sozzi, Fabiola B.; Danzi, Gian Battista
- Abstract
A 42-year-old man presented at our attention with chest pain. His cardiac risk factors were smoking habit and family history of coronary artery disease. At the ECG, a mild ST-segment elevation in the inferior leads was shown. A normal left ventricular function was demonstrated at the echocardiography. An emergency coronary angiography was performed, and an extensive thrombosis of the right coronary artery and midleft anterior descending coronary artery was visualized. A primary angioplasty with thrombus aspiration and direct stenting of both sites followed. Biochemical analysis revealed a high plasma homocysteine level with a homozygotic anomaly of the 5,10-methylenetetrahydrofolate reductase. Currently, a nine-month followup negative for cardiac events is recorded.
- Subjects
THROMBOSIS; METHYLENETETRAHYDROFOLATE reductase; HEART disease risk factors; ANGIOPLASTY; CORONARY arteries; ANGIOGRAPHY
- Publication
Cardiology Research & Practice, 2011, p1
- ISSN
2090-8016
- Publication type
Article
- DOI
10.4061/2011/856479