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Phosphodiesterase 5 inhibitor treatment and survival in interstitial lung disease pulmonary hypertension: A Bayesian retrospective observational cohort study.
Published in:
Respirology, 2023, v. 28, n. 3, p. 262, doi. 10.1111/resp.14378
By:
- Dawes, Timothy J. W.;
- McCabe, Colm;
- Dimopoulos, Konstantinos;
- Stewart, Iain;
- Bax, Simon;
- Harries, Carl;
- Samaranayake, Chinthaka B.;
- Kempny, Aleksander;
- Molyneaux, Philip L.;
- Seitler, Samuel;
- Semple, Thomas;
- Li, Wei;
- George, Peter M.;
- Kouranos, Vasileios;
- Chua, Felix;
- Renzoni, Elisabetta A.;
- Kokosi, Maria;
- Jenkins, Gisli;
- Wells, Athol U.;
- Wort, Stephen J.
Publication type:
Article
Year in review 2017: Interstitial lung disease, pulmonary vascular disease and sleep.
Published in:
Respirology, 2018, v. 23, n. 4, p. 421, doi. 10.1111/resp.13273
By:
- Piper, Amanda J.;
- Wort, Stephen J.;
- Renzoni, Elisabetta A.;
- Kouranos, Vasileios
Publication type:
Article
Eisenmenger syndrome: current perspectives.
Published in:
Research Reports in Clinical Cardiology, 2017, v. 8, p. 1, doi. 10.2147/RRCC.S117838
By:
- Nashat, Heba;
- Kempny, Aleksander;
- McCabe, Colm;
- Price, Laura C.;
- Harries, Carl;
- Alonso-Gonzalez, Rafael;
- Gatzoulis, Michael A.;
- Wort, Stephen J.;
- Dimopoulos, Konstantinos
Publication type:
Article
BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030075
By:
- Park, John E. S.;
- Shao, Dongmin;
- Upton, Paul D.;
- deSouza, Patricia;
- Adcock, Ian M.;
- Davies, Rachel J.;
- Morrell, Nicholas W.;
- Griffiths, Mark J. D.;
- Wort, Stephen J.
Publication type:
Article
The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension.
Published in:
PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009526
By:
- Harrington, Louise S.;
- Moreno, Laura;
- Reed, Anna;
- Wort, Stephen J.;
- Desvergne, Béatrice;
- Garland, Christopher;
- Lan Zhao;
- Mitchell, Jane A.
Publication type:
Article
Machine learning algorithms estimating prognosis and guiding therapy in adult congenital heart disease: data from a single tertiary centre including 10 019 patients.
Published in:
European Heart Journal, 2019, v. 40, n. 13, p. 1069, doi. 10.1093/eurheartj/ehy915
By:
- Diller, Gerhard-Paul;
- Kempny, Aleksander;
- Babu-Narayan, Sonya V;
- Henrichs, Marthe;
- Brida, Margarita;
- Uebing, Anselm;
- Lammers, Astrid E;
- Baumgartner, Helmut;
- Li, Wei;
- Wort, Stephen J;
- Dimopoulos, Konstantinos;
- Gatzoulis, Michael A
Publication type:
Article
Endogenously Released Endothelin-1 from Human Pulmonary Artery Smooth Muscle Promotes Cellular Proliferation.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2001, v. 25, n. 1, p. 104, doi. 10.1165/ajrcmb.25.1.4331
By:
- Wort, Stephen J.;
- Woods, Mandy;
- Warner, Timothy D.;
- Evans, Timothy W.;
- Mitchell, Jane A.
Publication type:
Article
Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension.
Published in:
2022
By:
- Rhodes, Christopher J.;
- Wharton, John;
- Swietlik, Emilia M.;
- Harbaum, Lars;
- Girerd, Barbara;
- Coghlan, J. Gerry;
- Lordan, James;
- Church, Colin;
- Pepke-Zaba, Joanna;
- Toshner, Mark;
- Wort, Stephen J.;
- Kiely, David G.;
- Condliffe, Robin;
- Lawrie, Allan;
- Gräf, Stefan;
- Montani, David;
- Boucly, Athénaïs;
- Sitbon, Olivier;
- Humbert, Marc;
- Howard, Luke S.
Publication type:
journal article
Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome.
Published in:
2020
By:
- Rhodes, Christopher J.;
- Otero-Núñez, Pablo;
- Wharton, John;
- Swietlik, Emilia M.;
- Kariotis, Sokratis;
- Harbaum, Lars;
- Dunning, Mark J.;
- Elinoff, Jason M.;
- Errington, Niamh;
- Thompson, A. A. Roger;
- Iremonger, James;
- Coghlan, J. Gerry;
- Corris, Paul A.;
- Howard, Luke S.;
- Kiely, David G.;
- Church, Colin;
- Pepke-Zaba, Joanna;
- Toshner, Mark;
- Wort, Stephen J.;
- Desai, Ankit A.
Publication type:
journal article
Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
Published in:
2015
By:
- Price, Laura C.;
- Dongmin Shao;
- Chao Meng;
- Perros, Frederic;
- Garfield, Benjamin E.;
- Jie Zhu;
- Montani, David;
- Dorfmuller, Peter;
- Humbert, Marc;
- Adcock, Ian M.;
- Wort, Stephen J.;
- Shao, Dongmin;
- Meng, Chao;
- Zhu, Jie
Publication type:
journal article
miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.
Published in:
PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0229409
By:
- Connolly, Martin;
- Garfield, Benjamin E.;
- Crosby, Alexi;
- Morrell, Nick W.;
- Wort, Stephen J.;
- Kemp, Paul R.
Publication type:
Article
EmPHasis-10 score for the assessment of quality of life in various types of pulmonary hypertension and its relation to outcome.
Published in:
European Journal of Preventive Cardiology, 2019, v. 26, n. 12, p. 1338, doi. 10.1177/2047487318819161
By:
- Favoccia, Carla;
- Kempny, Aleksander;
- Yorke, Janelle;
- Armstrong, Iain;
- Price, Laura C;
- McCabe, Colm;
- Harries, Carl;
- Wort, Stephen J;
- Dimopoulos, Konstantinos
Publication type:
Article
framework of deep learning networks provides expert-level accuracy for the detection and prognostication of pulmonary arterial hypertension.
Published in:
European Heart Journal - Cardiovascular Imaging, 2022, v. 23, n. 11, p. 1447, doi. 10.1093/ehjci/jeac147
By:
- Diller, Gerhard-Paul;
- Vidal, Maria Luisa Benesch;
- Kempny, Aleksander;
- Kubota, Kana;
- Li, Wei;
- Dimopoulos, Konstantinos;
- Arvanitaki, Alexandra;
- Lammers, Astrid E;
- Wort, Stephen J;
- Baumgartner, Helmut;
- Orwat, Stefan;
- Gatzoulis, Michael A
Publication type:
Article
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.
Published in:
Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aao4583
By:
- Michelakis, Evangelos D.;
- Gurtu, Vikram;
- Webster, Linda;
- Barnes, Gareth;
- Watson, Geoffrey;
- Howard, Luke;
- Cupitt, John;
- Paterson, Ian;
- Thompson, Richard B.;
- Chow, Kelvin;
- O'Regan, Declan P.;
- Lan Zhao;
- Wharton, John;
- Kiely, David G.;
- Kinnaird, Adam;
- Boukouris, Aristeidis E.;
- White, Chris;
- Nagendran, Jayan;
- Freed, Darren H.;
- Wort, Stephen J.
Publication type:
Article
Bosentan in Pulmonary Hypertension Associated with Fibrotic Idiopathic Interstitial Pneumonia.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 2, p. 208, doi. 10.1164/rccm.201403-0446OC
By:
- Corte, Tamera J.;
- Keir, Gregory J.;
- Dimopoulos, Konstantinos;
- Howard, Luke;
- Corris, Paul A.;
- Parfitt, Lisa;
- Foley, Claire;
- Yanez-Lopez, Monica;
- Babalis, Daphne;
- Marino, Philip;
- Maher, Toby M.;
- Renzoni, Elizabeth A.;
- Spencer, Lisa;
- Elliot, Charlie A.;
- Birring, Surinder S.;
- O'Reilly, Katherine;
- Gatzoulis, Michael A.;
- Wells, Athol U.;
- Wort, Stephen J.
Publication type:
Article
Bosentan in Pulmonary Hypertension associated with Fibrotic Idiopathic Interstitial Pneumonia (BPHIT).
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 2, p. E1, doi. 10.1164/rccm.201403-0446oc
By:
- Corte, Tamera J.;
- Keir, Gregory J.;
- Dimopoulos, Konstantinos;
- Howard, Luke;
- Corris, Paul A.;
- Parfitt, Lisa;
- Foley, Claire;
- Yanez-Lopez, Monica;
- Babalis, Daphne;
- Marino, Philip;
- Maher, Toby M.;
- Renzoni, Elizabeth A.;
- Spencer, Lisa;
- Elliot, Charlie A.;
- Birring, Surrinder;
- O'Reilly, Katherine;
- Gatzoulis, Michael A.;
- Wells, Athol U.;
- Wort, Stephen. J.
Publication type:
Article
Cardiac remodelling amongst adults with various aetiologies of pulmonary arterial hypertension including Eisenmenger syndrome--implications on survival and the role of right ventricular transverse strain.
Published in:
European Heart Journal - Cardiovascular Imaging, 2017, v. 18, n. 11, p. 1262, doi. 10.1093/ehjci/jew277
By:
- Moceri, Pamela;
- Bouvier, Priscille;
- Baudouy, Delphine;
- Dimopoulos, Konstantinos;
- Cerboni, Pierre;
- Wort, Stephen J.;
- Doyen, Denis;
- Schouver, Elie-Dan;
- Gibelin, Pierre;
- Senior, Roxy;
- Gatzoulis, Michael A.;
- Ferrari, Emile;
- Wei Li
Publication type:
Article
Year in review 2016: Interstitial lung disease, pulmonary vascular disease, pulmonary function, paediatric lung disease, cystic fibrosis and sleep.
Published in:
Respirology, 2017, v. 22, n. 5, p. 1022, doi. 10.1111/resp.13080
By:
- Jee, Adelle S.;
- Corte, Tamera J.;
- Wort, Stephen J.;
- Eves, Neil D.;
- Wainwright, Claire E.;
- Piper, Amanda
Publication type:
Article
Year in review 2015: Interstitial lung disease, pulmonary vascular disease, pulmonary function, sleep and ventilation, cystic fibrosis and paediatric lung disease.
Published in:
Respirology, 2016, v. 21, n. 3, p. 556, doi. 10.1111/resp.12749
By:
- Jo, Helen E.;
- Corte, Tamera J.;
- Wort, Stephen J.;
- Eves, Neil D.;
- Piper, Amanda;
- Wainwright, Claire
Publication type:
Article
Pulmonary function vascular index predicts prognosis in idiopathic interstitial pneumonia.
Published in:
Respirology, 2012, v. 17, n. 4, p. 674, doi. 10.1111/j.1440-1843.2011.02121.x
By:
- CORTE, TAMERA J.;
- WORT, STEPHEN J.;
- MACDONALD, PETER S.;
- EDEY, ANTHONY;
- HANSELL, DAVID M.;
- RENZONI, ELISABETTA;
- MAHER, TOBY M.;
- NICHOLSON, ANDREW G.;
- BANDULA, STEVEN;
- BRESSER, PAUL;
- WELLS, ATHOL U.
Publication type:
Article
Pulmonary hypertension in sarcoidosis: A review.
Published in:
Respirology, 2011, v. 16, n. 1, p. 69, doi. 10.1111/j.1440-1843.2010.01872.x
By:
- Corte, Tamera J.;
- Wells, Athol U.;
- Nicholson, Andrew G.;
- Hansell, David M.;
- Wort, Stephen J.
Publication type:
Article
miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2018, v. 9, n. 2, p. 400, doi. 10.1002/jcsm.12266
By:
- Connolly, Martin;
- Paul, Richard;
- Farre‐Garros, Roser;
- Natanek, Samantha A.;
- Bloch, Susannah;
- Lee, Jen;
- Lorenzo, Jose P.;
- Patel, Harnish;
- Cooper, Cyrus;
- Sayer, Avan A.;
- Wort, Stephen J.;
- Griffiths, Mark;
- Polkey, Michael I.;
- Kemp, Paul R.
Publication type:
Article
miR‐322‐5p targets IGF‐1 and is suppressed in the heart of rats with pulmonary hypertension.
Published in:
FEBS Open Bio, 2018, v. 8, n. 3, p. 339, doi. 10.1002/2211-5463.12369
By:
- Connolly, Martin;
- Garfield, Benjamin E.;
- Crosby, Alexi;
- Morrell, Nick W.;
- Wort, Stephen J.;
- Kemp, Paul R.
Publication type:
Article
Pulmonary Arterial Hypertension: Iron Matters.
Published in:
Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00641
By:
- Ramakrishnan, Latha;
- Pedersen, Sofia L.;
- Toe, Quezia K.;
- Quinlan, Gregory J.;
- Wort, Stephen J.
Publication type:
Article
Pulmonary hypertension in the setting of interstitial lung disease: Approach to management and treatment. A consensus statement from the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative—Group 3 Pulmonary Hypertension
Published in:
Pulmonary Circulation, 2024, v. 14, n. 1, p. 1, doi. 10.1002/pul2.12310
By:
- Shlobin, Oksana A.;
- Shen, Eric;
- Wort, Stephen J.;
- Piccari, Lucilla;
- Scandurra, John A.;
- Hassoun, Paul M.;
- Nikkho, Sylvia M.;
- Nathan, Steven D.
Publication type:
Article
Pulmonary hemodynamics and transplant-free survival in sarcoidosis-associated pulmonary hypertension: Results from an international registry.
Published in:
Pulmonary Circulation, 2023, v. 13, n. 4, p. 1, doi. 10.1002/pul2.12297
By:
- Gayen, Shameek K.;
- Baughman, Robert P.;
- Nathan, Steven D.;
- Wells, Athol U.;
- Kouranos, Vasilis;
- Alhamad, Esam H.;
- Culver, Daniel A.;
- Barney, Joseph;
- Carmoma, Eva M.;
- Cordova, Francis C.;
- Huitema, Marloes;
- Scholand, Mary Beth;
- Wijsenbeek, Marlies;
- Ganesh, Sivagini;
- Birring, Surinder S.;
- Price, Laura C.;
- Wort, Stephen J.;
- Shlobin, Oksana A.;
- Gupta, Rohit
Publication type:
Article
Clinical significance of pulmonary hypertension in interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute's innovative drug development initiative—Group 3 pulmonary hypertension.
Published in:
Pulmonary Circulation, 2022, v. 12, n. 3, p. 1, doi. 10.1002/pul2.12127
By:
- Nikkho, Sylvia M.;
- Richter, Manuel J.;
- Shen, Eric;
- Abman, Steven H.;
- Antoniou, Katerina;
- Chung, Jonathan;
- Fernandes, Peter;
- Hassoun, Paul;
- Lazarus, Howard M.;
- Olschewski, Horst;
- Piccari, Lucilla;
- Psotka, Mitchell;
- Saggar, Rajan;
- Shlobin, Oksana A.;
- Stockbridge, Norman;
- Vitulo, Patrizio;
- Vizza, Carmine Dario;
- Wort, Stephen J.;
- Nathan, Steven D.
Publication type:
Article
Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron‐regulatory elements: Potential implications for SARS‐CoV‐2 infection.
Published in:
Pulmonary Circulation, 2022, v. 12, n. 2, p. 1, doi. 10.1002/pul2.12068
By:
- Toe, Quezia K.;
- Issitt, Theo;
- Mahomed, Abdul;
- Almaghlougth, Fatma;
- Bahree, Ishan;
- Sturge, Charles;
- Xueqi Hu;
- Panselinas, Ioannis;
- Burke‐Gaffney, Anne;
- Wort, Stephen J. c.;
- Quinlan, Gregory John
Publication type:
Article
Positioning imatinib for pulmonary arterial hypertension: A phase I/II design comprising dose finding and single-arm efficacy.
Published in:
Pulmonary Circulation, 2021, v. 11, n. 4, p. 1, doi. 10.1177/20458940211052823
By:
- Wilkins, Martin R.;
- Mckie, Mikel A.;
- Law, Martin;
- Roussakis, Andreas A.;
- Harbaum, Lars;
- Church, Colin;
- Coghlan, J Gerry;
- Condliffe, Robin;
- Howard, Luke S;
- Kiely, David G;
- Lordan, Jim;
- Rothman, Alexander;
- Suntharalingam, Jay;
- Toshner, Mark;
- Wort, Stephen J;
- Villar, Sofía S.
Publication type:
Article
Rescue therapy with thrombolysis in patients with severe COVID-19-associated acute respiratory distress syndrome.
Published in:
Pulmonary Circulation, 2020, v. 10, n. 4, p. 1, doi. 10.1177/2045894020973906
By:
- Price, Laura C.;
- Garfield, Benjamin;
- Bleakley, Caroline;
- Keeling, Archie G.M.;
- Mcfadyen, Charles;
- McCabe, Colm;
- Ridge, Carole A.;
- Wort, Stephen J.;
- Price, Susanna;
- Arachchillage, Deepa J.
Publication type:
Article
Chemical and biological assessment of metal organic frameworks (MOFs) in pulmonary cells and in an acute in vivo model: relevance to pulmonary arterial hypertension therapy.
Published in:
Pulmonary Circulation, 2017, v. 7, n. 3, p. 643, doi. 10.1177/2045893217710224
By:
- Mohamed, Nura A.;
- Davies, Robert P.;
- Lickiss, Paul D.;
- Ahmetaj-Shala, Blerina;
- Reed, Daniel M.;
- Gashaw, Hime H.;
- Saleem, Hira;
- Freeman, Gemma R.;
- George, Peter M.;
- Wort, Stephen J.;
- Morales-Cano, Daniel;
- Barreira, Bianca;
- Tetley, Teresa D.;
- Chester, Adrian H.;
- Yacoub, Magdi H.;
- Kirkby, Nicholas S.;
- Moreno, Laura;
- Mitchell, Jane A.
Publication type:
Article
Outcome of cardiac surgery in patients with congenital heart disease in England between 1997 and 2015.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178963
By:
- Kempny, Aleksander;
- Dimopoulos, Konstantinos;
- Uebing, Anselm;
- Diller, Gerhard-Paul;
- Rosendahl, Ulrich;
- Belitsis, George;
- Gatzoulis, Michael A.;
- Wort, Stephen J.
Publication type:
Article

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