We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of Aerobic Exercise Alone or in Conjunction With Diet on Liver Function, Insulin Resistance and Lipids in Non-Alcoholic Fatty Liver Disease.
- Authors
Mohammad Rahimi, Gholam Rasul; Attarzadeh Hosseini, Seyyed Reza
- Abstract
Background: Physical exercises are the first step of therapy for people with non-alcoholic fatty liver disease (NAFLD). Objective: The purpose of this meta-analysis is to evaluate the efficacy of aerobic exercise training with or without diet to ameliorate liver function, insulin resistance, and lipids in adults. Data sources: We searched relevant databases up to 10 June 2021 for conducting a systematic review and meta-analysis of controlled trials lasting 4 or more weeks that investigated the effects of aerobic exercise alone or accompanied by diet on change in liver enzymes, intrahepatic fat (IHF), insulin resistance, and lipids. Results: Sixteen studies including 2255 participants were included. There was a significant pooled weighted mean differences (MD) for the comparison between aerobic exercise versus control in alanine aminotransferase (ALT; p = 0.003), aspartate aminotransferase (AST; p = 0.006), IHF (p = 0.0004), body mass (p = 0.0003), and body mass index (p = 0.004). Moreover, there was a significant pooled MD for the comparison between aerobic exercise plus diet versus control in ALT (p < 0.0001), AST (p = 0.01), IHF (p = 0.02), GGT (p < 0.00001), insulin (p < 0.0001), HOMA-IR (p < 0.00001), body mass (p < 0.0001), and BMI (p = 0.01). Conclusion: Our findings demonstrate a role for aerobic exercise with and without diet protocol as a therapeutic purpose, and suggest that evaluation of aerobic training levels and aerobic training prescription plus diet should be routine in NAFLD.
- Subjects
LIVER physiology; ONLINE information services; CINAHL database; AEROBIC exercises; META-analysis; MEDICAL information storage &; retrieval systems; DIET; NON-alcoholic fatty liver disease; DESCRIPTIVE statistics; MEDLINE; INSULIN resistance; LIPIDS
- Publication
Biological Research for Nursing, 2022, Vol 24, Issue 2, p259
- ISSN
1099-8004
- Publication type
Article
- DOI
10.1177/10998004211068026