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- Title
Trigona Honey as a Potential Supplementary Therapy to Halt the Progression of Post-Stroke Vascular Cognitive Impairment.
- Authors
Sabarisah Hashim; Suhana Ahmad; Mohammad A. I. Al. Hatamleh; Mohd Zulkifli Mustafa; Mahaneem Mohamed; Rohimah Mohamud; Ramlah Kadir; Tuan Noorkorina Tuan Kub
- Abstract
Background: Vascular cognitive impairment (VCI) is a syndrome that includes all neurological disorders from mild cognitive impairment to dementia caused primarily by cerebrovascular disease. The prevalence of post-stroke VCI reported between 36 to 67 % of survivors. Objective: This perspective review is to predict the potential effect of Trigona honey in halting the progression of VCI. Method: Based on its rich content of phenolic compounds, Trigona honey could assist in regulation of oxidative stress, which attenuated free radical-mediated molecular destruction. This mechanism could prevent neuroinflammation and promote memory, learning, cognitive functions and protect against neurotoxin-induced neuronal injury. Besides, this antioxidant activity of Trigona honey could results in rapid decline in the levels of inflammatory biomarkers, and thus maintains healthier white matter microstructure in brain. Conclusion: Therefore, the use of Trigona honey to enhance cognitive performance would be an interesting target for the future studies. The biochemical impact of Trigona honey makes it a potential complementary remedy to decrease the neuroinflammation and prevent the rapid progression of post-stroke VCI.
- Subjects
THERAPEUTIC use of honey; DISEASE progression; COGNITION disorders; MEMORY; BIOMARKERS; STROKE; PHENOLS; ANTIOXIDANTS; DIETARY supplements; OXIDATIVE stress; LEARNING; WHITE matter (Nerve tissue); NEURITIS; DISEASE complications
- Publication
International Medical Journal, 2021, Vol 28, Issue 3, p335
- ISSN
1341-2051
- Publication type
Article