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- Title
Assessment of ovarian reserve using anti-Müllerian hormone levels in benign gynecologic conditions and surgical interventions: a systematic narrative review.
- Authors
Akira Iwase; Tomoko Nakamura; Tatsuo Nakahara; Maki Goto; Fumitaka Kikkawa
- Abstract
The usefulness of anti-Müllerian hormone (AMH) for the quantitative evaluation of ovarian reserve has been established. Therefore, serum AMH has been recently applied to the assessment of ovarian reserve outside infertility treatment. We conducted a computer-based search, using keywords, through the PubMed database from inception until May 2014 and summarized available studies evaluating ovarian damage caused by gynecologic diseases, such as endometriosis and ovarian tumor, as well as surgical interventions, such as cystectomy and uterine artery embolization (UAE), to discuss the usefulness of serum AMH. Most of the studies demonstrated a decline of serum AMH levels after cystectomy for endometriomas. It is not conclusive whether electrocoagulation or suturing is preferable. The effects of other gynecologic diseases and interventions, such as hysterectomy and UAE, on ovarian reserve are controversial. Serum AMH levels should be considered in determining the indication and selection of operative methods for benign gynecologic conditions.
- Subjects
OVARIAN reserve; ANTI-Mullerian hormone; UTERINE artery; THERAPEUTIC embolization; CYSTECTOMY; HYSTERECTOMY
- Publication
Reproductive Biology & Endocrinology, 2014, Vol 12, Issue 1, p50
- ISSN
1477-7827
- Publication type
Article
- DOI
10.1186/1477-7827-12-125