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- Title
Gold Nanoparticles Grown on Ionic Liquid-Functionalized Single-Walled Carbon Nanotubes: New Materials for Photothermal Therapy.
- Authors
Meng, Lingjie; Niu, Lvye; Li, Ling; Lu, Qinghua; Fei, Zhaofu; Dyson, Paul J.
- Abstract
Gold nanoparticles were grown on single-walled carbon nanotubes (SWNTs) coated with a thiol-functionalized ionic liquid resulting in the formation of core-shell structures referred to as SWNT-IL-Au nanohybrid materials. The nanohybrid materials were characterized by high-resolution transmission electron microscopy (HR-TEM), Raman-, and UV/Vis absorption spectroscopy. The nanohybrid materials were found to enter lysosomes in HeLa cells and show negligible cytotoxicity. Interestingly, they have an enhanced NIR absorption that is effectively transferred into heat to cause localized hyperthermia, resulting in rapid cell death; overall, the material appears to have excellent properties for photothermal therapeutic applications.
- Publication
Chemistry - A European Journal, 2012, Vol 18, Issue 42, p13314
- ISSN
0947-6539
- Publication type
Article
- DOI
10.1002/chem.201201811