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- Title
Isolation and artificial production of atypical porcine pestivirus, using the swine-kidney-derived cell line SK-L.
- Authors
Shiokawa, Mai; Morita, Yui; Nagai, Makoto; Haritani, Makoto; Aoki, Hiroshi
- Abstract
Congenital tremor (CT) in piglets was first reported in 1922, and although the causative pathogen was unknown for many years, atypical porcine pestivirus (APPV) was recently shown to be the cause. APPV is difficult to isolate, and there have been few reports of APPV isolated from field materials. Here, we successfully isolated infectious particles from a tonsillar emulsion from a CT-affected piglet using the established swine-kidney-derived cell line SK-L. In addition, we produced APPV artificially using these cells. Thus, SK-L cells are useful for both isolation and artificial production of APPV.
- Publication
Archives of Virology, 2023, Vol 168, Issue 12, p1
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s00705-023-05919-y