We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Stem cells: Blood lines from embryo to adult.
- Authors
Ueno, Hiroo; Weissman, Irving L.
- Abstract
The article reports on a study providing a powerful evidence that yolk sac hematopoiesis does supply adult-forming cells as well. It is known that the yolk sac serves only the embryo, and that an independent origin of blood-forming stem cells begin in the region of the developing fetus known as the aorta-gonad-mesonephros (AGM). It was found that adult blood-forming cells in the AGM regions at least partly originated from Runx1-positive progenitors in the yolk sac.
- Subjects
HEMATOPOIESIS; YOLK sac; EMBRYONIC stem cells; HUMAN embryology; HUMAN embryos
- Publication
Nature, 2007, Vol 446, Issue 7139, p996
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/446996a