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- Title
Correlation of the Left Ventricular Systolic Dysfunction and Ventricular Depolarization in a Post-Infarction Model of Chronic Heart Failure.
- Authors
Roshchevskaya, I. M.; Suslonova, O. V.; Smirnova, S. L.; Ionova, E. O.; Vititnova, M. B.; Tsorin, I. B; Kryzhanovskii, S. A.
- Abstract
The body surface potential mapping of the heart during the period of ventricular depolarization and the inotropic function of the ventricles were studied in rats under conditions of a translational model of post-infarction chronic heart failure developed by us. We revealed a statistically significant (p<0.001) correlation between the left-ventricular ejection fraction and the values of the maximum positive and negative extrema of the cardioelectric field on the body surface of rats with post-infarction chronic heart failure caused by anterior transmural myocardial infarction. The calculated linear regression equations have high predictive efficiency, which makes it possible to use the amplitude characteristics of the heart cardioelectric field as a marker of the development of chronic heart failure.
- Subjects
LEFT ventricular dysfunction; VENTRICULAR dysfunction; HEART failure; ANTERIOR wall myocardial infarction; BODY surface mapping; HEART
- Publication
Bulletin of Experimental Biology & Medicine, 2024, Vol 176, Issue 4, p428
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-024-06040-z