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- Title
Integrins LFA-1 and Mac-1 and Cytokines IL-6 and IL-10 in High-Cancer Mice under the Influence of Phytoadaptogen.
- Authors
Bocharova, O.; Bocharov, E.; Karpova, R.; Il'enko, V.; Kazeev, I.; Baryshnikov, A.
- Abstract
The expression of leukocyte integrins LFA-1 and Mac-1 and cytokines IL-6 and IL-10 was studied in mice predisposed to spontaneous hepatocarcinomas. The effi cacy of a phytoadaptogen in correcting these parameters was evaluated. The role of adhesive interactions between immune cells and target cells in the recovery of antitumor regulatory mechanisms was estimated.
- Subjects
LIVER cancer; INTEGRINS; THERAPEUTIC use of cytokines; ANTINEOPLASTIC agents; LABORATORY mice; CELLULAR immunity; THERAPEUTICS
- Publication
Bulletin of Experimental Biology & Medicine, 2014, Vol 157, Issue 2, p258
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-014-2539-4