We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis, structure and herbicidal activity of substituted phenyl pyrazole derivatives.
- Authors
Zhou, Yuhan; Xue, Na; Wang, Guowei; Qu, Jingping
- Abstract
To search for novel Protox inhibitors, a series of phenyl and 1,4-benzoxazin-5-yl pyrazole derivatives were synthesised from 3-(4-chloro-2-fluoro-5-methoxyphenyl)-1-methyl-5-trifluoromethyl-1 H -pyrazole or its halogen substituted derivatives, via a serial of reactions that included nitration, reduction, acetylation, ring closure, methylation, etc. The single crystal of 2-(N-acetylacetamido)-6-chloro-3-[4-chloro-5-(trifluoromethyl)-1-methyl-1H -pyrazol-3-yl]-4-fluorophenyl acetate was prepared, and its structure was determined by X-ray analysis. The preliminary bioassay test shows that some of the compounds have high bioactivity. Especially, even at a low dosage of 150 g hm-2, 2-(N-acetylacetamido)-6-chloro-3-[4-chloro-5-(trifluoromethyl)-1-methyl-1 H -pyrazol-3-yl]-4-fluorophenyl acetate exhibited high activity, the inhibiting rate for both of the weeds reached above 90%.
- Subjects
CHEMICAL research; PYRAZOLES; X-rays; CHEMICAL synthesis; BIOLOGICAL assay; NITROFEN
- Publication
Journal of Chemical Research, 2010, Vol 34, Issue 12, p684
- ISSN
1747-5198
- Publication type
Article
- DOI
10.3184/030823410X12857507693337