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- Title
Haematological malignancies: at the forefront of immunotherapeutic innovation.
- Authors
Bachireddy, Pavan; Burkhardt, Ute E.; Rajasagi, Mohini; Wu, Catherine J.
- Abstract
The recent successes of cancer immunotherapies have stimulated interest in the potential widespread application of these approaches; haematological malignancies have provided both initial proofs of concept and an informative testing ground for various immune-based therapeutics. The immune-cell origin of many of the blood malignancies provides a unique opportunity both to understand the mechanisms of cancer immune responsiveness and immune evasion, and to exploit these mechanisms for therapeutic purposes.
- Subjects
CANCER treatment; IMMUNOTHERAPY; HEMATOLOGY; BLOOD diseases; IMMUNE response
- Publication
Nature Reviews Cancer, 2015, Vol 15, Issue 4, p201
- ISSN
1474-175X
- Publication type
Article
- DOI
10.1038/nrc3907