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- Title
Macular morphologic findings on optical coherence tomography after microincision vitrectomy for proliferative diabetic retinopathy.
- Authors
Murakami, Tomoaki; Uji, Akihito; Ogino, Ken; Unoki, Noriyuki; Yoshitake, Shin; Dodo, Yoko; Horii, Takahiro; Nishijima, Kazuaki; Yoshimura, Nagahisa
- Abstract
Purpose: To investigate macular morphology on spectral-domain optical coherence tomography (SD-OCT) images after microincision vitrectomy for vitreous hemorrhage associated with proliferative diabetic retinopathy (PDR). Methods: In this retrospective case series, 69 eyes (57 consecutive patients) that underwent 23-gauge microincision vitrectomy for vitreous hemorrhage due to PDR were investigated. Qualitative and quantitative characteristics on SD-OCT images [central retinal thickness, external limiting membrane (ELM), and the ellipsoid zone, epiretinal membranes involving the fovea, and hyperreflective foci at the fovea] were assessed 6 months postoperatively. Their association with the logarithm of the minimum angle of resolution visual acuity (logMAR VA) was evaluated. Results: The ELM was disrupted in 15 and the ellipsoid zone in 27 eyes, and associated significantly ( P < 0.001, for both comparisons) with poor visual outcomes 6 months postoperatively. Hyperreflective foci in the outer retinal layers were associated with either a disrupted ELM or ellipsoid zone and poor prognoses ( P < 0.001, for all comparisons). The accumulation of hyperreflective foci at the fovea in five eyes was correlated significantly ( P < 0.001) with poorer logMAR VA. Twenty-nine eyes had center-involved diabetic macular edema 6 months postoperatively, whereas the central thickness was not correlated with the logMAR VA ( R = −0.148, P = 0.224). Eight eyes with either epiretinal membrane on SD-OCT images had greater central thickness ( P = 0.003), although there were no differences in the logMAR VA between eyes with and without it ( P = 0.648). Conclusions: Foveal photoreceptor damage is associated with poor visual outcomes after microincision vitrectomy for vitreous hemorrhage due to PDR.
- Subjects
OPTICAL coherence tomography; VITRECTOMY; DIABETIC retinopathy; PHOTORECEPTORS; VISUAL acuity
- Publication
Japanese Journal of Ophthalmology, 2015, Vol 59, Issue 4, p236
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-015-0382-4