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- Title
Upregulation of protease-activated receptor-2 in keratinocytes by epidermal vascular endothelial growth factor in vitro and in vivo.
- Authors
Lee, Si‐Hyung; Kim, Ji Min; Lee, Sang Eun; Jeong, Se Kyoo; Lee, Seung Hun
- Abstract
The article discusses melasma and the increase in vascular endothelial growth factor (VEGF) and dermal vessels in melasma lesional skin. The upregulation of Protease-activated receptor-2 (PAR-2) by VEGF in keratinocytes, determining PAR-2 expression in melasma patients with elangiectasia, and efficiency of lasers as a treatment for melasma are also included.
- Subjects
MELANOSIS; VASCULAR endothelial growth factors; PROTEASE-activated receptors; TELANGIECTASIA; MEDICAL lasers; PATIENTS; THERAPEUTICS
- Publication
Experimental Dermatology, 2017, Vol 26, Issue 3, p286
- ISSN
0906-6705
- Publication type
Article
- DOI
10.1111/exd.13183