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- Title
Filaggrin-2 barrier protein inversely varies with skin inflammation.
- Authors
Seykora, John; Dentchev, Tzvete; Margolis, David J.
- Abstract
The article examines the immunohistochemical staining of filaggrin-2 gene (FLG2) in skin inflammation. The inverse association of the intensity of the staining with local inflammation is noted. The gene is found to be variably expressed in the stratum corneum of dermatitic skin. Variation in FLG2 immunohistochemical staining is also found with skin inflammatory response in those with atopic dermatitis.
- Subjects
FILAGGRIN; IMMUNOSTAINING; GENE expression; ATOPIC dermatitis; SKIN inflammation
- Publication
Experimental Dermatology, 2015, Vol 24, Issue 9, p720
- ISSN
0906-6705
- Publication type
Article
- DOI
10.1111/exd.12749