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- Title
Substance P activates human eosinophils.
- Authors
Raap, Mieke; Rüdrich, Urda; Ständer, Sonja; Gehring, Manuela; Kapp, Alexander; Raap, Ulrike
- Abstract
The article discusses the study on the expression of neurokinin-1 receptor (NK1R) and neurokinin-2 receptor (NK2R) and the functional effects of neuropeptide susbstance P (SP) on human peripheral blood eosinophils from atopic and non-atopic patients. It states that atopic and non-atopic patients shows tiny subpopulation of NK1R-positive eosinophils. It mentions that NK2R expression is higher in eosinophils from atopic patients.
- Subjects
SUBSTANCE P receptors; EOSINOPHILS; ATOPY; NEUROPEPTIDES; GENE expression
- Publication
Experimental Dermatology, 2015, Vol 24, Issue 7, p557
- ISSN
0906-6705
- Publication type
Article
- DOI
10.1111/exd.12717