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- Title
Topical vitamin D<sub>3</sub> (tacalcitol) for steroid-resistant prurigo.
- Authors
Katayama, I.; Miyazaki, Y.; Nishioka, K.
- Abstract
A topical vitamin D3 ointment (tacalcitol) was prescribed for patients with long-lasting pruriginous lesions (four with prurigo nodularis and seven with subacute prurigo, four of whom had atopic dermatitis). Seven of 11 cases had not responded to a topical steroid ointment and even to occlusive application of the ointment. Nine of 11 cases showed a significant clinical response to this new regimen within 4 weeks. Epidermal Fce R1(+) dendritic cells were increased in number in prurigo nodularis and reduced to normal level after the therapy. Topical vitamin D3 ointment might be an alternative therapy for steroid-resistant prurigo.
- Subjects
SKIN diseases; STEROID hormones; VITAMIN D; SKIN inflammation; THERAPEUTICS; ATOPIC dermatitis; STEROID drugs
- Publication
British Journal of Dermatology, 1996, Vol 135, Issue 2, p237
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1996.tb01153.x