We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Eosinophils, Basophils, and Neutrophils in Bullous Pemphigoid.
- Authors
Limberg, Maren M.; Weihrauch, Tobias; Gray, Natalie; Ernst, Nancy; Hartmann, Karin; Raap, Ulrike
- Abstract
Bullous pemphigoid (BP) is an autoimmune blistering skin disease, of which the incidence has increased in recent years. BP is characterized by circulating IgG and IgE autoantibodies against the hemidesmosomal proteins BP180 and BP230. Although autoantibodies trigger inflammatory cascades that lead to blister formation, effector cells and cell-mediated autoimmunity must also be considered as important factors in the pathogenesis of BP. The aim of this review is to outline the current knowledge on the role of eosinophils, basophils, and neutrophils in BP.
- Subjects
BULLOUS pemphigoid; EOSINOPHILS; BASOPHILS; NEUTROPHILS; AUTOANTIBODIES; SKIN diseases; DESMOGLEINS
- Publication
Biomolecules (2218-273X), 2023, Vol 13, Issue 7, p1019
- ISSN
2218-273X
- Publication type
Article
- DOI
10.3390/biom13071019