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- Title
A case of vanishing bile duct syndrome during treatment of microscopic polyangiitis with avacopan.
- Authors
Yamaguchi, Satoshi; Yamazaki, Miho; Kido, Toshiki; Hounoki, Hiroyuki; Muraishi, Nozomu; Tajiri, Kazuto; Tanaka, Shinichi; Tobe, Kazuyuki; Shinoda, Koichiro
- Abstract
The article describes the case of a 75-year-old woman diagnosed with hypertension, chronic gastritis and insomnia and was treated with amlodipine, mosapride, suvorexant and clotiazepam. Topics include her diagnosis of drug-induced vanishing bile duct syndrome (VBDS), clinical characteristics of VBDS, and the need for clinicians to be aware that serious drug-induced liver injuries, including VBDS can occur after avacopan treatment for antineutrophilic cytoplasmic antibody-associated vasculitis.
- Subjects
VASCULITIS; HYPERCHOLESTEREMIA; MICROSCOPIC polyangiitis; ANTINEUTROPHIL cytoplasmic antibodies; BILE duct diseases; COMPLEMENT (Immunology); HEMATURIA; PREDNISOLONE; ANTI-infective agents; CO-trimoxazole; PNEUMOCYSTIS pneumonia; PYELONEPHRITIS; COUGH; METHYLPREDNISOLONE; OSTEOPOROSIS; C-reactive protein; CHOLESTASIS
- Publication
Rheumatology, 2024, Vol 63, Issue 4, pe120
- ISSN
1462-0324
- Publication type
Case Study
- DOI
10.1093/rheumatology/kead285