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- Title
The Impact of Menopause on Bone Fusion after the Single-Level Anterior Cervical Discectomy and Fusion.
- Authors
Sung Bae Park; Chun Kee Chung; Sang Hyung Lee; Hee-Jin Yang; Young-Je Son; Young Seob Chung
- Abstract
Objective : To evaluate the successful fusion rate in postmenopausal women with single-level anterior cervical discectomy and successful fusion (ACDF) and identify the significant factors related to bone successful fusion in pre- and postmenopausal women. Methods : From July 2004 to December 2010, 108 consecutive patients who underwent single-level ACDF were prospectively selected as candidates. Among these, the charts and radiological data of 39 women were reviewed retrospectively. These 39 women were divided into two groups : a premenopausal group (n=11) and a postmenopausal group (n=28). To evaluate the significant factors affecting the successful fusion rate, the following were analyzed : the presence of successful fusion, successful fusion type, age, operated level, bone mineral density, graft materials, standalone cage or plating with autologous iliac bone, subsidence, adjacent segment degeneration, smoking, diabetes mellitus, and renal disease. Results : The successful fusion rates of the pre- and postmenopausal groups were 90.9% and 89.2%, respectively. There was no significant difference in the successful fusion rate or successful fusion type between the two groups. In the postmenopausal group, three patients (10.8%) had successful fusion failure. In the postmenopausal group, age and subsidence significantly affected the successful fusion rate (p=0.016 and 0.011, respectively), and the incidence of subsidence in patients with a cage was higher than that in patients with a plate (p=0.030). Conclusion : Menopausal status did not significantly affect bone successful fusion in patients with single-level ACDF. However, in older women with single-level ACDF, the combination of use of a cage and subsidence may unfavorably affect successful fusion.
- Subjects
POSTMENOPAUSE; CERVIX uteri surgery; BONE cells; MENOPAUSE; RETROSPECTIVE studies; NEUROSURGERY
- Publication
Journal of Korean Neurosurgical Society, 2013, Vol 54, Issue 6, p496
- ISSN
2005-3711
- Publication type
Article
- DOI
10.3340/jkns.2013.54.6.496