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- Title
Ontogeny of intestinal epithelial innate immune responses.
- Authors
Hornef, Mathias W.; Fulde, Marcus
- Abstract
Emerging evidence indicates that processes during postnatal development might significantly influence the establishment of mucosal host-microbial homeostasis. Developmental and adaptive immunological processes but also environmental and microbial exposure early after birth might thus affect disease susceptibility and health during adult life. The present review aims at summarizing the current understanding of the intestinal epithelial innate immune system and its developmental and adaptive changes after birth.
- Subjects
ONTOGENY; EPITHELIAL cells; NATURAL immunity; NEWBORN infant immunology; PATTERN recognition systems; PEPTIDE antibiotics
- Publication
Frontiers in Immunology, 2014, Vol 5, p1
- ISSN
1664-3224
- Publication type
Article
- DOI
10.3389/fimmu.2014.00474