OpenURL Connection Search

Select item for more details and to access through your institution.

A Decade of Genetic and Metabolomic Contributions to Type 2 Diabetes Risk Prediction.
Published in:
2017
By:
- Merino, Jordi;
- Udler, Miriam;
- Leong, Aaron;
- Meigs, James;
- Udler, Miriam S;
- Meigs, James B
Publication type:
journal article
A Long Non-coding RNA, LOC157273 , Is an Effector Transcript at the Chromosome 8p23.1- PPP1R3B Metabolic Traits and Type 2 Diabetes Risk Locus.
Published in:
Frontiers in Genetics, 2020, v. 11, p. 1, doi. 10.3389/fgene.2020.00615
By:
- Manning, Alisa K.;
- Goustin, Anton Scott;
- Kleinbrink, Erica L.;
- Thepsuwan, Pattaraporn;
- Cai, Juan;
- Ju, Donghong;
- Leong, Aaron;
- Udler, Miriam S.;
- Brown, James Bentley;
- Goodarzi, Mark O.;
- Rotter, Jerome I.;
- Sladek, Robert;
- Meigs, James B.;
- Lipovich, Leonard
Publication type:
Article
Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31625-5
By:
- Westerman, Kenneth E.;
- Majarian, Timothy D.;
- Giulianini, Franco;
- Jang, Dong-Keun;
- Miao, Jenkai;
- Florez, Jose C.;
- Chen, Han;
- Chasman, Daniel I.;
- Udler, Miriam S.;
- Manning, Alisa K.;
- Cole, Joanne B.
Publication type:
Article
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30931-2
By:
- Agrawal, Saaket;
- Wang, Minxian;
- Klarqvist, Marcus D. R.;
- Smith, Kirk;
- Shin, Joseph;
- Dashti, Hesam;
- Diamant, Nathaniel;
- Choi, Seung Hoan;
- Jurgens, Sean J.;
- Ellinor, Patrick T.;
- Philippakis, Anthony;
- Claussnitzer, Melina;
- Ng, Kenney;
- Udler, Miriam S.;
- Batra, Puneet;
- Khera, Amit V.
Publication type:
Article
Genetic counseling in diabetes mellitus: A practice resource of the National Society of Genetic Counselors.
Published in:
Journal of Genetic Counseling, 2024, v. 33, n. 3, p. 493, doi. 10.1002/jgc4.1744
By:
- Maloney, Kristin A.;
- Mizerik, Elizabeth;
- King, Robin H.;
- McGinnis, Erin M.;
- Perkowitz, Susan;
- Diamonstein, Callie J.;
- Schmanski, Andrew A.;
- Saliganan, Sheila;
- Shipper, Andrea G.;
- Udler, Miriam S.;
- Guan, Yue;
- Pollin, Toni I.
Publication type:
Article
Polycystic Ovary Syndrome Physiologic Pathways Implicated Through Clustering of Genetic Loci.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 4, p. 968, doi. 10.1210/clinem/dgad664
By:
- Stamou, Maria I;
- Smith, Kirk T;
- Kim, Hyunkyung;
- Balasubramanian, Ravikumar;
- Gray, Kathryn J;
- Udler, Miriam S
Publication type:
Article
Bioinformatics pipeline for the systematic mining genomic and proteomic variation linked to rare diseases: The example of monogenic diabetes.
Published in:
PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0300350
By:
- Kuznetsova, Ksenia G.;
- Vašíček, Jakub;
- Skiadopoulou, Dafni;
- Molnes, Janne;
- Udler, Miriam;
- Johansson, Stefan;
- Njølstad, Pål Rasmus;
- Manning, Alisa;
- Vaudel, Marc
Publication type:
Article
The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.
Published in:
Diabetologia, 2023, v. 66, n. 7, p. 1273, doi. 10.1007/s00125-023-05912-9
By:
- Huerta-Chagoya, Alicia;
- Schroeder, Philip;
- Mandla, Ravi;
- Deutsch, Aaron J.;
- Zhu, Wanying;
- Petty, Lauren;
- Yi, Xiaoyan;
- Cole, Joanne B.;
- Udler, Miriam S.;
- Dornbos, Peter;
- Porneala, Bianca;
- DiCorpo, Daniel;
- Liu, Ching-Ti;
- Li, Josephine H.;
- Szczerbiński, Lukasz;
- Kaur, Varinderpal;
- Kim, Joohyun;
- Lu, Yingchang;
- Martin, Alicia;
- Eizirik, Decio L.
Publication type:
Article
High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease.
Published in:
Diabetologia, 2023, v. 66, n. 3, p. 495, doi. 10.1007/s00125-022-05848-6
By:
- Kim, Hyunkyung;
- Westerman, Kenneth E.;
- Smith, Kirk;
- Chiou, Joshua;
- Cole, Joanne B.;
- Majarian, Timothy;
- von Grotthuss, Marcin;
- Kwak, Soo Heon;
- Kim, Jaegil;
- Mercader, Josep M.;
- Florez, Jose C.;
- Gaulton, Kyle;
- Manning, Alisa K.;
- Udler, Miriam S.
Publication type:
Article
Phenotypic and genetic classification of diabetes.
Published in:
Diabetologia, 2022, v. 65, n. 11, p. 1758, doi. 10.1007/s00125-022-05769-4
By:
- Deutsch, Aaron J.;
- Ahlqvist, Emma;
- Udler, Miriam S.
Publication type:
Article
Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes.
Published in:
Diabetologia, 2022, v. 65, n. 5, p. 790, doi. 10.1007/s00125-022-05653-1
By:
- Walker, Venexia M.;
- Vujkovic, Marijana;
- Carter, Alice R.;
- Davies, Neil M.;
- Udler, Miriam S.;
- Levin, Michael G.;
- Davey Smith, George;
- Voight, Benjamin F.;
- Gaunt, Tom R.;
- Damrauer, Scott M.
Publication type:
Article
A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies.
Published in:
Journal of the Endocrine Society, 2023, v. 7, n. 11, p. 1, doi. 10.1210/jendso/bvad123
By:
- Srinivasan, Shylaja;
- Wu, Peitao;
- Mercader, Josep M;
- Udler, Miriam S;
- Porneala, Bianca C;
- Bartz, Traci M;
- Floyd, James S;
- Sitlani, Colleen;
- Guo, Xiquing;
- Haessler, Jeffrey;
- Kooperberg, Charles;
- Liu, Jun;
- Ahmad, Shahzad;
- Duijn, Cornelia van;
- Liu, Ching-Ti;
- Goodarzi, Mark O;
- Florez, Jose C;
- Meigs, James B;
- Rotter, Jerome I;
- Rich, Stephen S
Publication type:
Article
386 A novel truncating variant of EBF2 disrupts human adipocyte differentiation in lipodystrophy syndromes: an example of a discovery from a clinical translational pipeline.
Published in:
2023
By:
- Foss-Freitas, Maria C.;
- Wys, Noel;
- Udler, Miriam;
- Pais, Lynne;
- Rocha, Andre Monteiro da;
- MacDougald, Ormond A.;
- Oral, Elif A.;
- Chun, Tae-Hwa
Publication type:
Abstract
Statistical evidence for high‐penetrance MODY‐causing genes in a large population‐based cohort.
Published in:
Endocrinology, Diabetes & Metabolism, 2022, v. 5, n. 6, p. 1, doi. 10.1002/edm2.372
By:
- Billings, Liana K.;
- Shi, Zhuqing;
- Resurreccion, W. Kyle;
- Wang, Chi‐Hsiung;
- Wei, Jun;
- Pollin, Toni I.;
- Udler, Miriam S.;
- Xu, Jianfeng
Publication type:
Article
Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer.
Published in:
International Journal of Cancer, 2009, v. 125, n. 11, p. 2687, doi. 10.1002/ijc.24678
By:
- Udler, Miriam S.;
- Azzato, Elizabeth M.;
- Healey, Catherine S.;
- Ahmed, Shahana;
- Pooley, Karen A.;
- Greenberg, David;
- Shah, Mitul;
- Teschendorff, Andrew E.;
- Caldas, Carlos;
- Dunning, Alison M.;
- Ostrander, Elaine A.;
- Caporaso, Neil E.;
- Easton, Douglas;
- Pharoah, Paul D.
Publication type:
Article
Initial Insights into the Genetic Variation Associated with Metformin Treatment Failure in Youth with Type 2 Diabetes.
Published in:
Pediatric Diabetes, 2023, p. 1, doi. 10.1155/2023/8883199
By:
- Srinivasan, Shylaja;
- Chen, Ling;
- Udler, Miriam;
- Todd, Jennifer;
- Kelsey, Megan M.;
- Haymond, Morey W.;
- Arslanian, Silva;
- Zeitler, Philip;
- Gubitosi-Klug, Rose;
- Nadeau, Kristen J.;
- Kutney, Katherine;
- White, Neil H.;
- Li, Josephine H.;
- Perry, James A.;
- Kaur, Varinderpal;
- Brenner, Laura;
- Mercader, Josep M.;
- Dawed, Adem;
- Pearson, Ewan R.;
- Yee, Sook-Wah
Publication type:
Article
Algorithmic identification of atypical diabetes in electronic health record (EHR) systems.
Published in:
PLoS ONE, 2022, v. 17, n. 12, p. 1, doi. 10.1371/journal.pone.0278759
By:
- Cromer, Sara J.;
- Chen, Victoria;
- Han, Christopher;
- Marshall, William;
- Emongo, Shekina;
- Greaux, Evelyn;
- Majarian, Tim;
- Florez, Jose C.;
- Mercader, Josep;
- Udler, Miriam S.
Publication type:
Article
Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine.
Published in:
Endocrine Reviews, 2019, v. 40, n. 6, p. 1500, doi. 10.1210/er.2019-00088
By:
- Udler, Miriam S;
- McCarthy, Mark I;
- Florez, Jose C;
- Mahajan, Anubha
Publication type:
Article
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.
Published in:
2018
By:
- Udler, Miriam S.;
- Kim, Jaegil;
- von Grotthuss, Marcin;
- Bonàs-Guarch, Sílvia;
- Cole, Joanne B.;
- Chiou, Joshua;
- null, null;
- Boehnke, Michael;
- Laakso, Markku;
- Atzmon, Gil;
- Glaser, Benjamin;
- Mercader, Josep M.;
- Gaulton, Kyle;
- Flannick, Jason;
- Getz, Gad;
- Florez, Jose C.;
- Christopher D. Anderson on behalf of METASTROKE and the ISGC
Publication type:
journal article
Fine scale mapping of the breast cancer 16q12 locus.
Published in:
Human Molecular Genetics, 2010, v. 19, n. 12, p. 2507, doi. 10.1093/hmg/ddq122
By:
- Udler, Miriam S.;
- Ahmed, Shahana;
- Healey, Catherine S.;
- Meyer, Kerstin;
- Struewing, Jeffrey;
- Maranian, Melanie;
- Kwon, Erika M.;
- Zhang, Jinghui;
- Tyrer, Jonathan;
- Karlins, Eric;
- Platte, Radka;
- Kalmyrzaev, Bolot;
- Dicks, Ed;
- Field, Helen;
- Maia, Ana-Teresa;
- Prathalingam, Radhika;
- Teschendorff, Andrew;
- McArthur, Stewart;
- Doody, David R.;
- Luben, Robert
Publication type:
Article
FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 9, p. 1692, doi. 10.1093/hmg/ddp078
By:
- Udler, Miriam S.;
- Meyer, Kerstin B.;
- Pooley, Karen A.;
- Karlins, Eric;
- Struewing, Jeffery P.;
- Zhang, Jinghui;
- Doody, David R.;
- MacArthur, Stewart;
- Tyrer, Jonathan;
- Pharoah, Paul D.;
- Luben, Robert;
- Bernstein, Leslie;
- Kolonel, Laurence N.;
- Henderson, Brian E.;
- Le Marchand, Loic;
- Ursin, Giske;
- Press, Michael F.;
- Brennan, Paul;
- Sangrajrang, Suleeporn;
- Gaborieau, Valerie
Publication type:
Article
Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes.
Published in:
Diabetes Care, 2023, v. 46, n. 8, p. 1541, doi. 10.2337/dc23-0353
By:
- Deutsch, Aaron J.;
- Schroeder, Philip H.;
- Mandla, Ravi;
- Kang, Sarah;
- Erenler, Feyza;
- Mercader, Josep M.;
- Udler, Miriam S.;
- Florez, Jose C.;
- Brenner, Laura N.
Publication type:
Article
Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity.
Published in:
Diabetes Care, 2023, v. 46, n. 5, p. 944, doi. 10.2337/dc22-1954
By:
- Cromer, Sara J.;
- Lakhani, Chirag M.;
- Mercader, Josep M.;
- Majarian, Timothy D.;
- Schroeder, Philip;
- Cole, Joanne B.;
- Florez, Jose C.;
- Patel, Chirag J.;
- Manning, Alisa K.;
- Burnett-Bowie, Sherri-Ann M.;
- Merino, Jordi;
- Udler, Miriam S.
Publication type:
Article
Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms.
Published in:
Diabetes Care, 2023, v. 46, n. 4, p. 794, doi. 10.2337/dc22-1833
By:
- Deutsch, Aaron J.;
- Stalbow, Lauren;
- Majarian, Timothy D.;
- Mercader, Josep M.;
- Manning, Alisa K.;
- Florez, Jose C.;
- Loos, Ruth J.F.;
- Udler, Miriam S.
Publication type:
Article
Evaluating the power to discriminate between highly correlated SNPs in genetic association studies.
Published in:
Genetic Epidemiology, 2010, v. 34, n. 5, p. 463, doi. 10.1002/gepi.20504
By:
- Udler, Miriam S.;
- Tyrer, Jonathan;
- Easton, Douglas F.
Publication type:
Article
Genetic determinants of daytime napping and effects on cardiometabolic health.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20585-3
By:
- Dashti, Hassan S.;
- Daghlas, Iyas;
- Lane, Jacqueline M.;
- Huang, Yunru;
- Udler, Miriam S.;
- Wang, Heming;
- Ollila, Hanna M.;
- Jones, Samuel E.;
- Kim, Jaegil;
- Wood, Andrew R.;
- 23andMe Research Team;
- Agee, Michelle;
- Auton, Adam;
- Bell, Robert K.;
- Bryc, Katarzyna;
- Clark, Sarah K.;
- Elson, Sarah L.;
- Fletez-Brant, Kipper;
- Fontanillas, Pierre;
- Furlotte, Nicholas A.
Publication type:
Article
Type 2 Diabetes: Multiple Genes, Multiple Diseases.
Published in:
2019
By:
- Udler, Miriam S.
Publication type:
journal article
Increased Genetic Risk for β-Cell Failure Is Associated With β-Cell Function Decline in People With Prediabetes.
Published in:
Diabetes, 2024, v. 73, n. 8, p. 1352, doi. 10.2337/db23-0761
By:
- Billings, Liana K.;
- Jablonski, Kathleen A.;
- Pan, Qing;
- Florez, Jose C.;
- Franks, Paul W.;
- Goldberg, Ronald B.;
- Hivert, Marie-France;
- Kahn, Steven E.;
- Knowler, William C.;
- Lee, Christine G.;
- Merino, Jordi;
- Huerta-Chagoya, Alicia;
- Mercader, Josep M.;
- Raghavan, Sridharan;
- Shi, Zhuqing;
- Srinivasan, Shylaja;
- Xu, Jianfeng;
- Udler, Miriam S.
Publication type:
Article
325-OR: Genetic and Socioeconomic Factors Are Independently Associated with Type 2 Diabetes.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-325-OR
By:
- CROMER, SARA JANE;
- LAKHANI, CHIRAG M.;
- MERCADER, JOSEP M.;
- MAJARIAN, TIM;
- FLOREZ, JOSE C.;
- MANNING, ALISA;
- MERINO, JORDI;
- UDLER, MIRIAM
Publication type:
Article
249-OR: Type 2 Diabetes (T2D) Genetic Clusters for Association with Glycemic Responses to Intervention for Diabetes Prevention.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-249-OR
By:
- BILLINGS, LIANA K.;
- JABLONSKI, KATHLEEN A.;
- FRANKS, PAUL W.;
- GOLDBERG, RONALD B.;
- HIVERT, MARIE-FRANCE;
- KAHN, STEVEN E.;
- KNOWLER, WILLIAM C.;
- LEE, CHRISTINE;
- MERINO, JORDI;
- RAGHAVAN, SRIDHARAN;
- SRINIVASAN, SHYLAJA;
- XU, JIANFENG;
- FLOREZ, JOSE C.;
- UDLER, MIRIAM
Publication type:
Article
1124-P: Clinical and Genetic Models Assess the Probability of Type 1 Diabetes (T1D) among Patients with Nonclassic Diabetes Features.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1124-P
By:
- BILLINGS, LIANA K.;
- SHI, ZHUQING;
- RESURRECCION, W. KYLE;
- QAMAR, ARMAN;
- WANG, CHI-HSIUNG;
- WEI, JUN;
- POLLIN, TONI I.;
- UDLER, MIRIAM;
- XU, JIANFENG
Publication type:
Article
Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering.
Published in:
2021
By:
- Powe, Camille E.;
- Udler, Miriam S.;
- Hsu, Sarah;
- Allard, Catherine;
- Kuang, Alan;
- Manning, Alisa K.;
- Perron, Patrice;
- Bouchard, Luigi;
- Lowe Jr., William L.;
- Scholtens, Denise;
- Florez, Jose C.;
- Hivert, Marie-France;
- Lowe, William L Jr
Publication type:
journal article
Defining Heterogeneity Among Women With Gestational Diabetes Mellitus.
Published in:
2020
By:
- Powe, Camille E.;
- Hivert, Marie-France;
- Udler, Miriam S.
Publication type:
journal article
1649-P: Effect of Fasting Insulin-Derived Gene Variant Clusters on Cardiometabolic Traits.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1649-P
By:
- SEVILLA, MAGDALENA;
- UDLER, MIRIAM;
- KIM, HYUNKYUNG;
- HSU, SARAH;
- MEIGS, JAMES B.;
- MANNING, ALISA
Publication type:
Article
1644-P: High Throughput Approach Enables Expanded Clustering of Type 2 Diabetes Genetic Loci Informed by Phenotypic Associations.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1644-P
By:
- KIM, HYUNKYUNG;
- VON GROTTHUSS, MARCIN;
- MERCADER, JOSEP M.;
- CHIOU, JOSHUA;
- GAULTON, KYLE J.;
- MANNING, ALISA;
- FLOREZ, JOSE C.;
- UDLER, MIRIAM
Publication type:
Article
1453-P: Adaption of the ACMG/AMP Variant Interpretation Guidelines for GCK, HNF1A, HNF4A-MODY: Recommendations from the ClinGen Monogenic Diabetes Expert Panel.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1453-P
By:
- ZHANG, HAICHEN;
- MALONEY, KRISTIN A.;
- BARBETTI, FABRIZIO;
- GREELEY, SIRI ATMA W.;
- KETTUNEN, JARNO L.T.;
- MIRANDA, JOSÉ P.;
- MIRSHAHI, UYENLINH L.;
- MOLNES, JANNE;
- MURPHY, RINKI;
- NAYLOR, ROCHELLE N.;
- PAKYZ, RUTH E.;
- PHILIPSON, LOUIS H.;
- PRUDENTE, SABRINA;
- TUOMI, TIINAMAIJA;
- UDLER, MIRIAM;
- COLCLOUGH, KEVIN;
- JENG, LINDA;
- POLLIN, TONI I.
Publication type:
Article
240-OR: Combining Type 2 Diabetes Polygenic Scores Improves Prediction in 36,000 European and Non-European Participants in the Partners Healthcare Biobank.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-240-OR
By:
- MERCADER, JOSEP M.;
- FLOREZ, JOSE C.;
- LEONG, AARON;
- KAUR, VARINDERPAL;
- UDLER, MIRIAM;
- MEIGS, JAMES B.;
- PORNEALA, BIANCA
Publication type:
Article
2264-PUB: Progress in Curating Gene–Disease Relationships by the ClinGen Monogenic Diabetes Expert Panel.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2264-PUB
By:
- POLLIN, TONI I.;
- MAYERS, MEGAN A.;
- GREELEY, SIRI ATMA W.;
- MALONEY, KRISTIN A.;
- NAYLOR, ROCHELLE N.;
- PAKYZ, RUTH E.;
- PATEL, KASHYAP A.;
- UDLER, MIRIAM;
- ZHANG, HAICHEN;
- COLCLOUGH, KEVIN;
- THAXTON, COURTNEY
Publication type:
Article
193-OR: Physiology-Informed Type 2 Diabetes Genetic Clusters and Gestational Diabetes.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-193-OR
By:
- POWE, CAMILLE E.;
- UDLER, MIRIAM;
- HSU, SARAH;
- KUANG, ALAN;
- ALLARD, CATHERINE;
- MANNING, ALISA;
- BOUCHARD, LUIGI;
- PERRON, PATRICE;
- FLOREZ, JOSE C.;
- LOWE JR., WILLIAM;
- SCHOLTENS, DENISE;
- HIVERT, MARIE-FRANCE
Publication type:
Article
354-OR: Physiologic Pathways in Pregnancy Glycemic Regulation Implicated through Genetic Clustering Analysis.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-354-OR
By:
- POWE, CAMILLE E.;
- UDLER, MIRIAM;
- ALLARD, CATHERINE;
- KIM, JAEGIL;
- PERRON, PATRICE;
- BOUCHARD, LUIGI;
- FLOREZ, JOSE C.;
- HIVERT, MARIE-FRANCE
Publication type:
Article

Found: 40