Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleNew synthesis of ethambutol and related α,β-acetylenic amino alcohols.AuthorsMavrov, M.; Simirskaya, N.AbstractEthambutol was obtained in 35% overall yield in three steps by enantiomeric separation of rac-2-benzylamino-3-butyl-1-ol, alkylation of the S-enantiomer with 1,2-dibromoethane, and catalytic N-debenzylation.SubjectsETHAMBUTOL; DRUG synthesis; ETHYLENE dibromide; ACETYLENE compounds; AMINO alcohols; ENANTIOMERSPublicationPharmaceutical Chemistry Journal, 2013, Vol 46, Issue 12, p730ISSN0091-150XPublication typeArticleDOI10.1007/s11094-013-0880-y