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- Title
Characteristics of Anemia in Malignant Disorders in Sana'a - Yemen.
- Authors
Almorish, Mohammed Abdul Wahid
- Abstract
Introduction: Anemia is associated with its own set of debilitating signs and symptoms and can have a significant effect on morbidity and mortality. These are aggravated in patients with malignant disorders. Objective: To evaluate the characteristics of anemia in Yemeni patients with malignant disorders in Sana'a. Methods: This is a prospective study, involved 60 patients with malignant disorders (30 males and 30 females) referred from National Oncology Center, Al-Thawra Hospital and The Military Hospital in Sana'a for six months (from Jun. 1st to Dec. 30th, 2017). Results: Anemia among solid tumors was higher than in hematological malignancies. Males showed higher anemia with hematological malignancies while females showed higher anemia with solid tumors. Common cancers with anemia were GIT cancers, breast and leukemias. In males, common cancers with anemia were GIT cancers, leukemias and lymphomas, while in females, breast cancers, GIT cancers and gynecological cancers. The common morphology of anemia was normocytic normochromic followed by microcytic hypochromic pictures. The common grades of anemia were grade 1 and 2, severe degree anemia was in 21.7%. Anemic patients with cancers showed significantly lower mean Hb, RBC count, Htc and MCHC, and significantly higher mean serum ferritin and B12 concentrations. Conclusion: This study concluded that anemia is a common finding in cancer patients and attributed to increased RBCs destruction and cytokins mediated decreased production and recommended further studies.
- Subjects
YEMEN (Republic); ANEMIA; MILITARY hospitals; SYMPTOMS; HEMATOLOGIC malignancies; DISEASES
- Publication
Pan Arab Journal of Oncology, 2019, Vol 12, Issue 1, p24
- ISSN
2070-254X
- Publication type
Article