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- Title
Cardiac left heart morphology and function in newborns with intrauterine growth restriction: relevance for long-term assessment.
- Authors
Zaharie, Gabriela C.; Hăşmăşanu, Monica G.; Blaga, Ligia; Matyas, Melinda; Mureșan, Daniel; Bolboacă, Sorana D.; Zaharie, Gabriela Corina; Hasmasanu, Monica; Muresan, Daniel; Bolboaca, Sorana Daniela
- Abstract
<bold>Aim: </bold>To asses the cardiac morphology and functional changes specific for newborns from intrauterine growth restriction (IUGR) pregnancies.<bold>Material and Method: </bold>A cohort of IUGR infants were evaluated by serial echocardiographies at delivery and at the first and six months follow-ups. IUGR newborn delivery status was compared to that of newborns in the control group according to gestational age (AGA).<bold>Results: </bold>Left heart measurements were significantly lower in IUGR newborns compared to AGA babies. Left ventricular size increased at follow-up inthe IUGR group (p<0.05). Systolic dysfunction (the myocardial performance index (MPI)> 0.47) was identified in 40% of the neonates in the IUGR group (16/40), respectively 4.76% in the control group. IUGR neonates had a significantly increased proportion of systolic malfunction (p=0.004).<bold>Conclusion: </bold> IUGR patients had reduced left ventricle dimensions compared to AGA babies. The MPI stands out as a marker of leftheart function in newborns. Systolic dysfunction was a hallmark of the cardiac adaptation in IUGR neonates.
- Subjects
FETAL growth retardation; LEFT heart ventricle; NEWBORN infant physiology; NEWBORN infant health; MORPHOLOGY; ECHOCARDIOGRAPHY
- Publication
Medical Ultrasonography, 2019, Vol 21, Issue 1, p62
- ISSN
1844-4172
- Publication type
journal article
- DOI
10.11152/mu-1667