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- Title
Aggressive Chemotherapy for Acute Leukemia Relapsed after Bone Marrow Transplantation: A Second Chance?
- Authors
Sica, S.; Di Mario, A.; Pagano, L.; Etuk, B.; Salutari, P.; Leone, G.
- Abstract
Eight patients, 5 with acute non lymphoid leukemia and 3 with lymphoid leukemia, were treated at relapse after bone marrow transplantation (BMT; 4 autologous BMT and 4 allogeneic BMT). Of these, 2 relapsed within 3 months after BMT (2 allogeneic BMT) and 6 (2 allogeneic and 4 autologous BMT) after more than 9 months after BMT. The 2 patients relapsing early showed no response to treatment and died. Five out of 6 patients relapsing late achieved complete remission (4 of them with intensive chemotherapy). Four patients are currently alive. Aggressive combination chemotherapy can produce long-term survival in selected patients relapsed after BMT. Copyright © 1992 S. Karger AG, Basel
- Publication
Acta Haematologica, 1992, Vol 87, Issue 4, p173
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000204754