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Activation of cathepsin B, secreted by a colorectal cancer cell line requires low pH and is mediated by cathepsin D.
Published in:
International Journal of Cancer, 1996, v. 67, n. 4, p. 547, doi. 10.1002/(SICI)1097-0215(19960807)67:4<547::AID-IJC14>3.0.CO;2-4
By:
- Van Der Stappen, Jos W. J.;
- Williams, Ann C.;
- Maciewicz, Rose A.;
- Paraskeva, Christos
Publication type:
Article
Immunodetection of cathepsins b and l present in and secreted from human pre-malignant and malignant colorectal tumour cell lines.
Published in:
International Journal of Cancer, 1989, v. 43, n. 3, p. 478, doi. 10.1002/ijc.2910430323
By:
- Maciewicz, Rose A.;
- John Wardale, R.;
- Etherington, David J.;
- Paraskeva, Christos
Publication type:
Article
Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023371
By:
- Valdes, Ana M.;
- Styrkarsdottir, Unnur;
- Doherty, Michael;
- Morris, David L.;
- Mangino, Massimo;
- Tamm, Agu;
- Doherty, Sally A.;
- Kisand, Kalle;
- Kerna, Irina;
- Tamm, Ann;
- Wheeler, Margaret;
- Maciewicz, Rose A.;
- Weiya Zhang;
- Muir, Kenneth R.;
- Dennison, Elaine M.;
- Hart, Deborah J.;
- Metrustry, Sarah;
- Jonsdottir, Ingileif;
- Jonsson, Gudbjorn F.;
- Jonsson, Helgi
Publication type:
Article
Large‐scale plasma proteomics can reveal distinct endotypes in chronic obstructive pulmonary disease and severe asthma.
Published in:
Clinical & Translational Allergy, 2021, v. 11, n. 10, p. 1, doi. 10.1002/clt2.12091
By:
- Suzuki, Masaru;
- Cole, John J.;
- Konno, Satoshi;
- Makita, Hironi;
- Kimura, Hiroki;
- Nishimura, Masaharu;
- Maciewicz, Rose A.
Publication type:
Article
Association of Beta-Blocker Use With Less Prevalent Joint Pain and Lower Opioid Requirement in People With Osteoarthritis.
Published in:
Arthritis Care & Research, 2017, v. 69, n. 7, p. 1076, doi. 10.1002/acr.23091
By:
- Valdes, Ana M.;
- Abhishek, Abhishek;
- Muir, Kenneth;
- Zhang, Weiya;
- Maciewicz, Rose A.;
- Doherty, Michael
Publication type:
Article
Association of Beta-Blocker Use With Less Prevalent Joint Pain and Lower Opioid Requirement in People With Osteoarthritis.
Published in:
2016
By:
- Valdes, Ana M;
- Abhishek, Abhishek;
- Muir, Kenneth;
- Zhang, Weiya;
- Maciewicz, Rose A;
- Doherty, Michael
Publication type:
journal article
Distribution of finger nodes and their association with underlying radiographic features of osteoarthritis.
Published in:
Arthritis Care & Research, 2012, v. 64, n. 4, p. 533, doi. 10.1002/acr.21586
By:
- Rees, Frances;
- Doherty, Sally;
- Hui, Michelle;
- Maciewicz, Rose;
- Muir, Kenneth;
- Zhang, Weiya;
- Doherty, Michael
Publication type:
Article
Self-reported knee malalignment in early adult life as an independent risk for knee chondrocalcinosis.
Published in:
Arthritis Care & Research, 2011, v. 63, n. 11, p. 1550, doi. 10.1002/acr.20593
By:
- Abhishek, Abhishek;
- Doherty, Sally;
- Maciewicz, Rose A.;
- Muir, Kenneth R.;
- Zhang, Weiya;
- Doherty, Michael
Publication type:
Article
Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.
Published in:
2011
By:
- Valdes, Ana M.;
- Arden, Nigel K.;
- Vaughn, Frances L.;
- Doherty, Sally A.;
- Leaverton, Paul E.;
- Zhang, Weiya;
- Muir, Kenneth R.;
- Rampersaud, Evadnie;
- Dennison, Elaine M.;
- Edwards, Mark H.;
- Jameson, Karen A.;
- Javaid, M. Kassim;
- Spector, Tim D.;
- Cooper, Cyrus;
- Maciewicz, Rose A.;
- Doherty, Michael
Publication type:
journal article
Role of the Na<sub>v</sub>1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.
Published in:
Arthritis Care & Research, 2011, v. 63, n. 3, p. 440, doi. 10.1002/acr.20375
By:
- Valdes, Ana M.;
- Arden, Nigel K.;
- Vaughn, Frances L.;
- Doherty, Sally A.;
- Leaverton, Paul E.;
- Zhang, Weiya;
- Muir, Kenneth R.;
- Rampersaud, Evadnie;
- Dennison, Elaine M.;
- Edwards, Mark H.;
- Jameson, Karen A.;
- Javaid, M. Kassim;
- Spector, Tim D.;
- Cooper, Cyrus;
- Maciewicz, Rose A.;
- Doherty, Michael
Publication type:
Article
Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study.
Published in:
Arthritis Research & Therapy, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13075-015-0534-4
By:
- Muthuri, Stella G.;
- Weiya Zhang;
- Maciewicz, Rose A.;
- Muir, Kenneth;
- Doherty, Michael
Publication type:
Article
The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case-control study.
Published in:
Arthritis Research & Therapy, 2014, v. 16, n. 1, p. 1, doi. 10.1186/ar4453
By:
- Abhishek, Abhishek;
- Doherty, Sally;
- Maciewicz, Rose;
- Muir, Kenneth;
- Zhang, Weiya;
- Doherty, Michael;
- Valdes, Anna M.
Publication type:
Article
Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis.
Published in:
Arthritis Research & Therapy, 2013, v. 15, n. 2, p. 52, doi. 10.1186/ar4214
By:
- Muthuri, Stella G;
- Doherty, Sally;
- Zhang, Weiya;
- Maciewicz, Rose A;
- Muir, Kenneth R;
- Doherty, Michael
Publication type:
Article
Chondrocalcinosis is common in the absence of knee involvement.
Published in:
Arthritis Research & Therapy, 2012, v. 14, n. 5, p. 4043, doi. 10.1186/ar4043
By:
- Abhishek, Abhishek;
- Doherty, Sally;
- Maciewicz, Rose;
- Muir, Kenneth;
- Weiya Zhang;
- Doherty, Michael
Publication type:
Article
Bone Area Provides a Responsive Outcome Measure for Bone Changes in Short-term Knee Osteoarthritis Studies.
Published in:
2016
By:
- Bowes, Michael A.;
- Maciewicz, Rose A.;
- Waterton, John C.;
- Hunter, David J.;
- Conaghan, Philip G.
Publication type:
journal article
Mapping pathogenesis of arthritis through small animal models.
Published in:
Rheumatology, 2012, v. 51, n. 11, p. 1931
By:
- Vincent, Tonia L.;
- Williams, Richard O.;
- Maciewicz, Rose;
- Silman, Alan;
- Garside, Paul
Publication type:
Article
Evaluation of a magnetic resonance biomarker of osteoarthritis disease progression: doxycycline slows tibial cartilage loss in the Dunkin Hartley guinea pig.
Published in:
International Journal of Experimental Pathology, 2009, v. 90, n. 2, p. 174, doi. 10.1111/j.1365-2613.2008.00634.x
By:
- Bowyer, Jonathan;
- Heapy, Chris G.;
- Flannelly, Joanne K.;
- Waterton, John C.;
- Maciewicz, Rose A.
Publication type:
Article
Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy.
Published in:
International Journal of Experimental Pathology, 2004, v. 85, n. 2, p. 85, doi. 10.1111/j.0959-9673.2004.00373.x
By:
- Potts, Wendy;
- Bowyer, Jonathan;
- Jones, Huw;
- Tucker, David;
- Freemont, Anthony J.;
- Millest, Andrew;
- Martin, Cohn;
- Vernon, Wendy;
- Neerunjun, Diane;
- Slynn, Gillian;
- Harper, Fiona;
- Maciewicz, Rose
Publication type:
Article
British Connective Tissue Society Meeting, York, 18--19 September 1997.
Published in:
1998
By:
- Kielty, Cay;
- Maciewicz, Rose;
- Gilbert, S. J.;
- Vaughan-Thomas, A.;
- Ovenstone, E.;
- Duance, V.C.;
- Murphy, L.I.;
- Fischer, D.;
- Chiquet-Ehrismann, R.;
- Mackie, E.J.;
- Spiers, S.;
- Canfield, A.E.;
- Davies, G.B.M.;
- Flannery, C.R.;
- Hughes, C.E.;
- Hiscock, D.R.R.;
- Little, C.B.;
- Caterson, B.;
- Thomas, S.
Publication type:
Abstract
Diurnal variation in the femoral articular cartilage of the knee in young adult humans.
Published in:
Magnetic Resonance in Medicine, 2000, v. 43, n. 1, p. 126, doi. 10.1002/(SICI)1522-2594(200001)43:1<126::AID-MRM15>3.0.CO;2-#
By:
- Waterton, John C.;
- Solloway, Stuart;
- Foster, John E.;
- Keen, Michael C.;
- Gandy, Stephen;
- Middleton, Brian J.;
- Maciewicz, Rose A.;
- Watt, Iain;
- Dieppe, Paul A.;
- Taylor, Christopher J.
Publication type:
Article
Lower Leptin/Adiponectin Ratio and Risk of Rapid Lung Function Decline in Chronic Obstructive Pulmonary Disease.
Published in:
Annals of the American Thoracic Society, 2014, v. 11, n. 10, p. 1511, doi. 10.1513/AnnalsATS.201408-351OC
By:
- Masaru Suzuki;
- Hironi Makita;
- Östling, Jörgen;
- Thomsen, Laura H.;
- Satoshi Konno;
- Katsura Nagai;
- Kaoruko Shimizu;
- Pedersen, Jesper H.;
- Ashraf, Haseem;
- Bruijnzeel, Piet L. B.;
- Maciewicz, Rose A.;
- Masaharu Nishimura
Publication type:
Article
Characterization of Fibrodysplasia in the Dog Following Inhibition of Metalloproteinases.
Published in:
Toxicologic Pathology, 2009, v. 37, n. 7, p. 860, doi. 10.1177/0192623309347909
By:
- Westwood, Russell;
- Scott, Robert C.;
- Somers, Rebecca L.;
- Coulson, Michelle;
- Maciewicz, Rose A.
Publication type:
Article
MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling.
Published in:
Cell Communication & Signaling, 2019, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12964-019-0378-7
By:
- Baturcam, Engin;
- Vollmer, Stefan;
- Schlüter, Holger;
- Maciewicz, Rose A.;
- Kurian, Nisha;
- Vaarala, Outi;
- Ludwig, Stephan;
- Cunoosamy, Danen Mootoosamy
Publication type:
Article
Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study.
Published in:
2014
By:
- McWilliams, Daniel F;
- Muthuri, Stella;
- Muir, Kenneth R;
- Maciewicz, Rose A;
- Zhang, Weiya;
- Doherty, Michael
Publication type:
journal article
Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts.
Published in:
BMC Bioinformatics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12859-021-04321-2
By:
- Cole, John J.;
- Faydaci, Bekir A.;
- McGuinness, David;
- Shaw, Robin;
- Maciewicz, Rose A.;
- Robertson, Neil A.;
- Goodyear, Carl S.
Publication type:
Article
Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.
Published in:
PLoS Genetics, 2016, v. 12, n. 10, p. 1, doi. 10.1371/journal.pgen.1006260
By:
- Castaño-Betancourt, Martha C.;
- Evans, Dan S.;
- Ramos, Yolande F. M.;
- Boer, Cindy G.;
- Metrustry, Sarah;
- Liu, Youfang;
- den Hollander, Wouter;
- van Rooij, Jeroen;
- Kraus, Virginia B.;
- Yau, Michelle S.;
- Mitchell, Braxton D.;
- Muir, Kenneth;
- Hofman, Albert;
- Doherty, Michael;
- Doherty, Sally;
- Zhang, Weiya;
- Kraaij, Robert;
- Rivadeneira, Fernando;
- Barrett-Connor, Elizabeth;
- Maciewicz, Rose A.
Publication type:
Article

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