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- Title
Successful Biodegradation of a Refractory Pharmaceutical Compound by an Indigenous Phenol-Tolerant <italic>Pseudomonas aeruginosa</italic> Strain.
- Authors
Hemidouche, Sabra; Favier, Lidia; Amrane, Abdeltif; Dabert, Patrick; Le Roux, Sophie; Sadaoui, Zahra
- Abstract
This study provides an alternative solution for the bioremediation of a recalcitrant pharmaceutical micropollutant. Clofibric acid (CLA) was chosen as target molecule, because of its environmental persistence and resistance to wastewater treatment technologies. The aim of this study was to investigate the potential of a phenol-resistant <italic>Pseudomonas aeruginosa</italic> strain isolated from the activated sludge to degrade CLA. In order to evaluate the effect of acclimation process with glucose as carbon co-substrate, two protocols were performed, in which the transfer of the inoculum is carried out either in the exponential growth phase or in the decline phase. The results showed a removal efficiency of CLA of 35% when cells in the decline phase were used for inoculation. In contrast, a very low removal yield (10%) was achieved when cells harvested in the exponential phase were used as inoculum. This work is the first one reporting on the capability of this bacterium to remove this drug. The obtained data showed that the isolated strain is able to degrade target molecule and might be a promising agent for the elimination of this refractory compound.
- Subjects
MICROPOLLUTANTS; CLOFIBRIC acid; PSEUDOMONAS aeruginosa; WASTEWATER treatment; ACTIVATED sludge process
- Publication
Water, Air & Soil Pollution, 2018, Vol 229, Issue 3, p1
- ISSN
0049-6979
- Publication type
Article
- DOI
10.1007/s11270-018-3684-6