We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Neuromuscular Control before and after Independent Walking Onset in Children with Cerebral Palsy.
- Authors
Bekius, Annike; Zandvoort, Coen S.; Kerkman, Jennifer N.; van de Pol, Laura A.; Vermeulen, R. Jeroen; Harlaar, Jaap; Daffertshofer, Andreas; Buizer, Annemieke I.; Dominici, Nadia; Iosa, Marco
- Abstract
Early brain lesions which produce cerebral palsy (CP) may affect the development of walking. It is unclear whether or how neuromuscular control, as evaluated by muscle synergy analysis, differs in young children with CP compared to typically developing (TD) children with the same walking ability, before and after the onset of independent walking. Here we grouped twenty children with (high risk of) CP and twenty TD children (age 6.5–52.4 months) based on their walking ability, supported or independent walking. Muscle synergies were extracted from electromyography data of bilateral leg muscles using non-negative matrix factorization. Number, synergies' structure and variability accounted for when extracting one (VAF1) or two (VAF2) synergies were compared between CP and TD. Children in the CP group recruited fewer synergies with higher VAF1 and VAF2 compared to TD children in the supported and independent walking group. The most affected side in children with asymmetric CP walking independently recruited fewer synergies with higher VAF1 compared to the least affected side. Our findings suggest that early brain lesions result in early alterations of neuromuscular control, specific for the most affected side in asymmetric CP.
- Subjects
CHILDREN with cerebral palsy; BRAIN damage; MATRIX decomposition; NONNEGATIVE matrices; LEG muscles
- Publication
Sensors (14248220), 2021, Vol 21, Issue 8, p2714
- ISSN
1424-8220
- Publication type
Article
- DOI
10.3390/s21082714