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Square-Wave Voltammetry as a Tool for Investigation of Doxorubicin Interactions with DNA Isolated from Neuroblastoma Cells.
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- Electroanalysis, 2009, v. 21, n. 3-5, p. 487, doi. 10.1002/elan.200804429
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- Article
The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells.
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- International Journal of Oncology, 2015, v. 47, n. 1, p. 343, doi. 10.3892/ijo.2015.2996
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- Article
Histone deacetylase inhibitors in cancer therapy. A review.
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- Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, 2014, v. 158, n. 2, p. 161, doi. 10.5507/bp.2013.085
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- Article
Analysis of covalent ellipticine- and doxorubicin-derived adducts in DNA of neuroblastoma cells by the <sup>32</sup>P-postlabeling technique.
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- Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, 2012, v. 156, n. 2, p. 115, doi. 10.5507/bp.2012.043
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- Article
THE ROLE OF BIOTRANSFORMATION ENZYMES IN THE DEVELOPMENT OF RENAL INJURY AND UROTHELIAL CANCER CAUSED BY ARISTOLOCHIC ACID: URGENT QUESTIONS AND DIFFICULT ANSWERS.
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- Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, 2009, v. 153, n. 1, p. 5, doi. 10.5507/bp.2009.001
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- Article
Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10479, doi. 10.3390/ijms221910479
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- Article
Benzo[ a ]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8062, doi. 10.3390/ijms22158062
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- Article
Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 14, p. 3392, doi. 10.3390/ijms20143392
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- Article
The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 1, p. 164, doi. 10.3390/ijms19010164
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- Article
DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 10, p. 2144, doi. 10.3390/ijms18102144
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- Article
Histone Deacetylase Inhibitors as Anticancer Drugs.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1414, doi. 10.3390/ijms18071414
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- Article
Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.
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- International Journal of Molecular Sciences, 2016, v. 17, n. 2, p. 213, doi. 10.3390/ijms17020213
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- Article
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 27561, doi. 10.3390/ijms161126047
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- Article
The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN™) Mice and Pure Enzymes.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 1, p. 284, doi. 10.3390/ijms16010284
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- Article
Modulation of Induced Cytotoxicity of Doxorubicin by Using Apoferritin and Liposomal Cages.
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- International Journal of Molecular Sciences, 2014, v. 15, n. 12, p. 22960, doi. 10.3390/ijms151222960
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- Article
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches.
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- International Journal of Molecular Sciences, 2014, v. 15, n. 6, p. 10271, doi. 10.3390/ijms150610271
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- Article
The Application of an Emerging Technique for Protein-Protein Interaction Interface Mapping: The Combination of Photo-Initiated Cross-Linking Protein Nanoprobes with Mass Spectrometry.
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- International Journal of Molecular Sciences, 2014, v. 15, n. 6, p. 9224, doi. 10.3390/ijms15069224
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- Article
A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 11, p. 21629, doi. 10.3390/ijms141121629
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- Article
Sarcosine as a Potential Prostate Cancer Biomarker--A Review.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 7, p. 13893, doi. 10.3390/ijms140713893
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- Article
Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 7, p. 13391, doi. 10.3390/ijms140713391
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- Article
The Role of Metallothionein in Oxidative Stress.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 3, p. 6044, doi. 10.3390/ijms14036044
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- Article
Doxorubicin interactions with bovine serum albumin revealed by microdialysis with on-line laser-induced fluorescence detection at subpicogram level.
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- Electrophoresis, 2015, v. 36, n. 11/12, p. 1282, doi. 10.1002/elps.201400564
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- Article
Study of DNA-ellipticine interaction by capillary electrophoresis with laser-induced fluorescence detection.
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- Electrophoresis, 2012, v. 33, n. 11, p. 1545, doi. 10.1002/elps.201200056
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- Article
Prostate tumor attenuation in the nu/nu murine model due to anti-sarcosine antibodies in folate-targeted liposomes.
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- Scientific Reports, 2016, p. 33379, doi. 10.1038/srep33379
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- Article
Chicken immunoglobulins for prophylaxis: Effect of inhaled antibodies on inflammatory parameters in rat airways.
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- Journal of Applied Biomedicine, 2015, v. 13, n. 1, p. 19, doi. 10.1016/j.jab.2014.04.003
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- Article
Automated assay of the potency of natural antioxidants using pipetting robot and spectrophotometry.
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- Journal of Applied Biomedicine, 2012, v. 10, n. 3, p. 155, doi. 10.2478/v10136-012-0006-y
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- Article
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[ a]pyrene in human livers.
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- Environmental & Molecular Mutagenesis, 2016, v. 57, n. 3, p. 229, doi. 10.1002/em.22001
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- Article
Apoferritin as an ubiquitous nanocarrier with excellent shelf life.
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- International Journal of Nanomedicine, 2017, v. 12, p. 2265, doi. 10.2147/IJN.S130267
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- Article
Sarcosine is a prostate epigenetic modifier that elicits aberrant methylation patterns through the SAMe‐Dnmts axis.
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- Molecular Oncology, 2019, v. 13, n. 5, p. 1002, doi. 10.1002/1878-0261.12439
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- Article
Aerobic biodegradation of dinitrophenols and their mixture in continuous operations by an immobilized mixed microbial community.
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- Clean Technologies & Environmental Policy, 2015, v. 17, n. 1, p. 287, doi. 10.1007/s10098-014-0772-1
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- Article
Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans.
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- Carcinogenesis, 2004, v. 25, n. 5, p. 833
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- Article
Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.
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- Carcinogenesis, 2002, v. 23, n. 4, p. 617, doi. 10.1093/carcin/23.4.617
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- Article
Fluorescence Characterization of Gold Modified Liposomes with Antisense N-myc DNA Bound to the Magnetisable Particles with Encapsulated Anticancer Drugs (Doxorubicin, Ellipticine and Etoposide).
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- Sensors (14248220), 2016, v. 16, n. 3, p. 290, doi. 10.3390/s16030290
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- Article
Fluorescent Cellular Assay for Screening Agents Inhibiting Pseudomonas aeruginosa Adherence.
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- Sensors (14248220), 2015, v. 15, n. 1, p. 1945, doi. 10.3390/s150101945
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- Article
Formation of DNA Adducts by Ellipticine and Its Micellar Form in Rats -- A Comparative Study.
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- Sensors (14248220), 2014, v. 14, n. 12, p. 22982, doi. 10.3390/s141222982
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- Article
Modern Micro and Nanoparticle-Based Imaging Techniques.
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- Sensors (14248220), 2012, v. 12, n. 11, p. 14792, doi. 10.3390/s121114792
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- Article
Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, Ec DOS and YddV, have profound effects on their flexibility.
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- FEBS Journal, 2014, v. 281, n. 23, p. 5208, doi. 10.1111/febs.13060
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- Article
The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 6, p. 448, doi. 10.1002/em.20642
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- Article
Mutagenic Potential of Nitrenium Ions of Nitrobenzanthrones: Correlation Between Theory and Experiment.
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- Environmental & Molecular Mutagenesis, 2008, v. 49, n. 8, p. 659, doi. 10.1002/em.20411
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- Article
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.
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- Carcinogenesis, 2008, v. 29, n. 3, p. 656
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- Article
Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.
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- Carcinogenesis, 2007, v. 28, n. 11, p. 2253, doi. 10.1093/carcin/bgm082
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- Article
Formation and persistence of DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in target and non-target organs after intratracheal instillation in rats.
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- Carcinogenesis, 2007, v. 28, n. 5, p. 1117, doi. 10.1093/carcin/bgl219
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- Publication type:
- Article
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine.
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- International Journal of Cancer, 2007, v. 120, n. 2, p. 243, doi. 10.1002/ijc.22247
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- Article
Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogen o-anisidine.
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- International Journal of Cancer, 2005, v. 116, n. 5, p. 667, doi. 10.1002/ijc.21122
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- Article
Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:Cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.
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- International Journal of Cancer, 2005, v. 113, n. 2, p. 189, doi. 10.1002/ijc.20564
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- Article
DNA adduct formation by the anticancer drug ellipticine in rats determined by <sup>32</sup>P postlabeling.
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- International Journal of Cancer, 2003, v. 107, n. 6, p. 885
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- Publication type:
- Article
Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer?
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- International Journal of Cancer, 2002, v. 101, n. 5, p. 500, doi. 10.1002/ijc.10602
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- Publication type:
- Article
Sarcosine influences apoptosis and growth of prostate cells via cell-type specific regulation of distinct sets of genes.
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- Prostate, 2018, v. 78, n. 2, p. 104, doi. 10.1002/pros.23450
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- Article
Relation of Exposure to Amino Acids Involved in Sarcosine Metabolic Pathway on Behavior of Non-Tumor and Malignant Prostatic Cell Lines.
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- Prostate, 2016, v. 76, n. 7, p. 679, doi. 10.1002/pros.23159
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- Article
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review.
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- Mutagenesis, 2002, v. 17, n. 4, p. 265, doi. 10.1093/mutage/17.4.265
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- Article