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- Title
Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives.
- Authors
Bersano, Anna; Gatti, Laura
- Abstract
In fact, not all individuals with common cerebrovascular risk factors develop a stroke event, and stroke can occur in subjects without cerebrovascular risk factors [[4]]. For a deeper understanding of the diverse pathological mechanisms and of the biological and molecular events that occur in stroke, and therefore for the development of novel or better tailored therapies, experimental animal models of ischemic stroke and in vitro cellular stroke models have been developed. Stroke is among the most prevalent causes of disability and is the second leading cause of death worldwide in Western countries [[1]]. Intracranial atherosclerosis with in situ thrombosis and small vessel disease are also important mechanisms of stroke, whereas cervical artery dissection is one of the most prevalent causes of stroke in younger patients [[3]].
- Subjects
STROKE; BLOOD-brain barrier; PATHOLOGICAL physiology; ATRIAL fibrillation; CEREBRAL amyloid angiopathy
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 19, p14848
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms241914848