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- Title
Carcino-Evo-Devo , A Theory of the Evolutionary Role of Hereditary Tumors.
- Authors
Kozlov, Andrei P.
- Abstract
A theory of the evolutionary role of hereditary tumors, or the carcino-evo-devo theory, is being developed. The main hypothesis of the theory, the hypothesis of evolution by tumor neofunctionalization, posits that hereditary tumors provided additional cell masses during the evolution of multicellular organisms for the expression of evolutionarily novel genes. The carcino-evo-devo theory has formulated several nontrivial predictions that have been confirmed in the laboratory of the author. It also suggests several nontrivial explanations of biological phenomena previously unexplained by the existing theories or incompletely understood. By considering three major types of biological development—individual, evolutionary, and neoplastic development—within one theoretical framework, the carcino-evo-devo theory has the potential to become a unifying biological theory.
- Subjects
PHENOMENOLOGICAL biology; TUMORS; MULTICELLULAR organisms
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 10, p8611
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms24108611