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Oxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific O -Glycosylation of Anterior Gradient Protein 2 (AGR2).
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5369, doi. 10.3390/ijms22105369
By:
- Pirro, Martina;
- Mohammed, Yassene;
- de Ru, Arnoud H.;
- Janssen, George M. C.;
- Tjokrodirijo, Rayman T. N.;
- Madunić, Katarina;
- Wuhrer, Manfred;
- van Veelen, Peter A.;
- Hensbergen, Paul J.;
- Greco, Viviana;
- Wessels, Hans J. C. T.
Publication type:
Article
N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5522, doi. 10.3390/ijms21155522
By:
- Pirro, Martina;
- Mohammed, Yassene;
- van Vliet, Sandra J.;
- Rombouts, Yoann;
- Sciacca, Agnese;
- de Ru, Arnoud H.;
- Janssen, George M. C.;
- Tjokrodirijo, Rayman T. N.;
- Wuhrer, Manfred;
- van Veelen, Peter A.;
- Hensbergen, Paul J.
Publication type:
Article
Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.831822
By:
- Laghmouchi, Aicha;
- Kester, Michel G. D.;
- Hoogstraten, Conny;
- Hageman, Lois;
- de Klerk, Wendy;
- Huisman, Wesley;
- Koster, Eva A. S.;
- de Ru, Arnoud H.;
- van Balen, Peter;
- Klobuch, Sebastian;
- van Veelen, Peter A.;
- Falkenburg, J. H. Frederik;
- Jedema, Inge
Publication type:
Article
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.
Published in:
Nature Biotechnology, 2022, v. 40, n. 4, p. 488, doi. 10.1038/s41587-021-01089-x
By:
- Ali, Muhammad;
- Giannakopoulou, Eirini;
- Li, Yingqian;
- Lehander, Madeleine;
- Virding Culleton, Stina;
- Yang, Weiwen;
- Knetter, Cathrine;
- Odabasi, Mete Can;
- Bollineni, Ravi Chand;
- Yang, Xinbo;
- Foldvari, Zsofia;
- Böschen, Maxi-Lu;
- Taraldsrud, Eli;
- Strønen, Erlend;
- Toebes, Mireille;
- Hillen, Amy;
- Mazzi, Stefania;
- de Ru, Arnoud H.;
- Janssen, George M. C.;
- Kolstad, Arne
Publication type:
Article
Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.
Published in:
PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128206
By:
- Hoelen, Hanneke;
- Zaldumbide, Arnaud;
- van Leeuwen, Wouter F.;
- Torfs, Ellen C. W.;
- Engelse, Marten A.;
- Hassan, Chopie;
- Lebbink, Robert Jan;
- de Koning, Eelco J.;
- Resssing, Maaike E.;
- de Ru, Arnoud H.;
- van Veelen, Peter A.;
- Hoeben, Rob C.;
- Roep, Bart O.;
- Wiertz, Emmanuel J. H. J.
Publication type:
Article
Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034649
By:
- Van Luijn, Marvin M.;
- Van de Loosdrecht, Arjan A.;
- Lampen, Margit H.;
- Van Veelen, Peter A.;
- Zevenbergen, Adri;
- Kester, Michel G. D.;
- De Ru, Arnoud H.;
- Ossenkoppele, Gert J.;
- Hall, Thorbald van;
- van Ham, S. Marieke
Publication type:
Article
Apparent Lack of BRAF <sup> V600E </sup> Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8<sup>+</sup> T Cells in Langerhans Cell Histiocytosis.
Published in:
Frontiers in Immunology, 2020, v. 10, p. 1, doi. 10.3389/fimmu.2019.03045
By:
- Kemps, Paul G.;
- Zondag, Timo C.;
- Steenwijk, Eline C.;
- Andriessen, Quirine;
- Borst, Jelske;
- Vloemans, Sandra;
- Roelen, Dave L.;
- Voortman, Lenard M.;
- Verdijk, Robert M.;
- van Noesel, Carel J. M.;
- Cleven, Arjen H. G.;
- Hawkins, Cynthia;
- Lang, Veronica;
- de Ru, Arnoud H.;
- Janssen, George M. C.;
- Haasnoot, Geert W.;
- Franken, Kees L. M. C.;
- van Eijk, Ronald;
- Solleveld-Westerink, Nienke;
- van Wezel, Tom
Publication type:
Article
Proteolytic activity of surface‐exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile.
Published in:
Molecular Microbiology, 2024, v. 122, n. 4, p. 413, doi. 10.1111/mmi.15300
By:
- Corver, Jeroen;
- Claushuis, Bart;
- Shamorkina, Tatiana M.;
- de Ru, Arnoud H.;
- van Leeuwen, Merle M.;
- Hensbergen, Paul J.;
- Smits, Wiep Klaas
Publication type:
Article
Non‐prime‐ and prime‐side profiling of Pro‐Pro endopeptidase specificity using synthetic combinatorial peptide libraries and mass spectrometry.
Published in:
FEBS Journal, 2024, v. 291, n. 17, p. 3820, doi. 10.1111/febs.17160
By:
- Claushuis, Bart;
- Cordfunke, Robert A.;
- de Ru, Arnoud H.;
- van Angeren, Jordy;
- Baumann, Ulrich;
- van Veelen, Peter A.;
- Wuhrer, Manfred;
- Corver, Jeroen;
- Drijfhout, Jan W.;
- Hensbergen, Paul J.
Publication type:
Article
PRAME and CTCFL-reactive TCRs for the treatment of ovarian cancer.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1121973
By:
- van Amerongen, Rosa A.;
- Tuit, Sander;
- Wouters, Anne K.;
- van de Meent, Marian;
- Siekman, Sterre L.;
- Meeuwsen, Miranda H.;
- Wachsmann, Tassilo L. A.;
- Remst, Dennis F. G.;
- Hagedoorn, Renate S.;
- van der Steen, Dirk M.;
- de Ru, Arnoud H.;
- Verdegaal, Els M. E.;
- van Veelen, Peter A.;
- Falkenburg, J. H. Frederik;
- Heemskerk, Mirjam H. M.
Publication type:
Article
Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia.
Published in:
2019
By:
- van der Lee, Dyantha I.;
- Reijmers, Rogier M.;
- Honders, Maria W.;
- Hagedoorn, Renate S.;
- de Jong, Rob C. M.;
- Kester, Michel G. D.;
- van der Steen, Dirk M.;
- de Ru, Arnoud H.;
- Kweekel, Christiaan;
- Bijen, Helena M.;
- Jedema, Inge;
- Veelken, Hendrik;
- van Veelen, Peter A.;
- Heemskerk, Mirjam H. M.;
- Falkenburg, J. H. Frederik;
- Griffioen, Marieke;
- de Jong, Rob Cm;
- Kester, Michel Gd;
- Heemskerk, Mirjam Hm
Publication type:
journal article
Specific T Cell Responses against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface.
Published in:
Proteomics, 2018, v. 18, n. 12, p. 1, doi. 10.1002/pmic.201700250
By:
- Bijen, Helena M.;
- Hassan, Chopie;
- Kester, Michel G. D.;
- Janssen, George M. C.;
- Hombrink, Pleun;
- de Ru, Arnoud H.;
- Drijfhout, Jan Wouter;
- Meiring, Hugo D.;
- de Jong, Ad P.;
- Falkenburg, J. H. Frederik;
- Jimenez, Connie R.;
- Heemskerk, Mirjam H. M.;
- van Veelen, Peter A.
Publication type:
Article
Ligandomes obtained from different HLA-class II-molecules are homologous for N- and C-terminal residues outside the peptide-binding cleft.
Published in:
Immunogenetics, 2019, v. 71, n. 8/9, p. 519, doi. 10.1007/s00251-019-01129-6
By:
- Kampstra, Arieke S.B.;
- van Heemst, Jurgen;
- Janssen, George M.;
- de Ru, Arnoud H.;
- van Lummel, Menno;
- van Veelen, Peter A.;
- Toes, René E.M.
Publication type:
Article
Hotspot DNA Methyltransferase 3A (DNMT3A) and Isocitrate Dehydrogenase 1 and 2 (IDH1/2) Mutations in Acute Myeloid Leukemia and Their Relevance as Targets for Immunotherapy.
Published in:
Biomedicines, 2024, v. 12, n. 5, p. 1086, doi. 10.3390/biomedicines12051086
By:
- Struckman, Nadine E.;
- de Jong, Rob C. M.;
- Honders, M. Willy;
- Smith, Sophie-Anne I.;
- van der Lee, Dyantha I.;
- Koutsoumpli, Georgia;
- de Ru, Arnoud H.;
- Mikesch, Jan-Henrik;
- van Veelen, Peter A.;
- Falkenburg, J. H. Frederik;
- Griffioen, Marieke
Publication type:
Article
Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques.
Published in:
Immunogenetics, 2013, v. 65, n. 12, p. 897, doi. 10.1007/s00251-013-0734-5
By:
- de Groot, Natasja G.;
- Heijmans, Corrine M. C.;
- de Ru, Arnoud H.;
- Hassan, Chopie;
- Otting, Nel;
- Doxiadis, Gaby G. M.;
- Koning, Frits;
- van Veelen, Peter A.;
- Bontrop, Ronald E.
Publication type:
Article
Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule.
Published in:
Immunogenetics, 2008, v. 60, n. 9, p. 551, doi. 10.1007/s00251-008-0310-6
By:
- Wiesner, Martina;
- Stepniak, Dariusz;
- De Ru, Arnoud H.;
- Moustakis, Antonis K.;
- Drijfhout, Jan W.;
- Papadopoulos, George K.;
- Van Veelen, Peter A.;
- Koning, Frits
Publication type:
Article
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48427-6
By:
- Salas-Lloret, Daniel;
- García-Rodríguez, Néstor;
- Soto-Hidalgo, Emily;
- González-Vinceiro, Lourdes;
- Espejo-Serrano, Carmen;
- Giebel, Lisanne;
- Mateos-Martín, María Luisa;
- de Ru, Arnoud H.;
- van Veelen, Peter A.;
- Huertas, Pablo;
- Vertegaal, Alfred C. O.;
- González-Prieto, Román
Publication type:
Article
Terminal α2,6-sialylation of epidermal growth factor receptor modulates antibody therapy response of colorectal cancer cells.
Published in:
Cellular Oncology (2211-3428), 2021, v. 44, n. 4, p. 835, doi. 10.1007/s13402-021-00606-z
By:
- Rodrigues, Joana G.;
- Duarte, Henrique O.;
- Gomes, Catarina;
- Balmaña, Meritxell;
- Martins, Álvaro M.;
- Hensbergen, Paul J.;
- de Ru, Arnoud H.;
- Lima, Jorge;
- Albergaria, André;
- van Veelen, Peter A.;
- Wuhrer, Manfred;
- Gomes, Joana;
- Reis, Celso A.
Publication type:
Article
Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain.
Published in:
Journal of Hematology & Oncology, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13045-023-01408-6
By:
- Meeuwsen, Miranda H.;
- Wouters, Anne K.;
- Wachsmann, Tassilo L. A.;
- Hagedoorn, Renate S.;
- Kester, Michel G. D.;
- Remst, Dennis F. G.;
- van der Steen, Dirk M.;
- de Ru, Arnoud H.;
- van Hees, Els P.;
- Kremer, Martijn;
- Griffioen, Marieke;
- van Veelen, Peter A.;
- Falkenburg, J. H. Frederik;
- Heemskerk, Mirjam H. M.
Publication type:
Article
Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane.
Published in:
European Journal of Immunology, 2004, v. 34, n. 1, p. 156, doi. 10.1002/eji.200324241
By:
- Verdijk, Pauline;
- van Veelen, Peter A.;
- de Ru, Arnoud H.;
- Hensbergen, Paul J.;
- Mizuno, Kensaku;
- Koerten, Henk K.;
- Koning, Frits;
- Tensen, Cornelis P.;
- Mommaas, A. Mieke
Publication type:
Article
Epitope Stealing as a Mechanism of Dominant Protection by HLA-DQ6 in Type 1 Diabetes.
Published in:
2019
By:
- van Lummel, Menno;
- Buis, David T. P.;
- Ringeling, Cherish;
- de Ru, Arnoud H.;
- Pool, Jos;
- Papadopoulos, George K.;
- van Veelen, Peter A.;
- Reijonen, Helena;
- Drijfhout, Jan W.;
- Roep, Bart O.
Publication type:
journal article
Discovery of a Selective Islet Peptidome Presented by the Highest-Risk HLA-DQ8trans Molecule.
Published in:
2016
By:
- van Lummel, Menno;
- van Veelen, Peter A.;
- de Ru, Arnoud H.;
- Pool, Jos;
- Nikolic, Tatjana;
- Laban, Sandra;
- Joosten, Antoinette;
- Drijfhout, Jan W.;
- Gómez-Touriño, Iria;
- Arif, Sefina;
- Aanstoot, Henk J.;
- Peakman, Mark;
- Roep, Bart O.
Publication type:
journal article
The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling.
Published in:
PLoS Pathogens, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.ppat.1011179
By:
- Treffers, Emmely E.;
- Tas, Ali;
- Scholte, Florine E. M.;
- de Ru, Arnoud H.;
- Snijder, Eric J.;
- van Veelen, Peter A.;
- van Hemert, Martijn J.
Publication type:
Article

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