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- Title
Paralytic Ileus and Prophylactic Gastrointestinal Motility Medication after Spinal Operation.
- Authors
Chang Hyun Oh; Gyu Yeul Ji; Seung Hwan Yoon; Dongkeun Hyun; Hyeong-chun Park; Yeo Ju Kim
- Abstract
Purpose: To investigate the prevalence of paralytic ileus after spinal operation in the supine or prone operative position and to determine the efficacy of prophylactic gastrointestinal motility medications in preventing symptomatic paralytic ileus after a spinal operation. Materials and Methods: All patients received spinal surgery in the supine or prone operative position. The study period was divided into two phases: first, to analyze the prevalence of radiographic and symptomatic paralytic ileus after a spinal operation, and second, to determine the therapeutic effects of prophylactic gastrointestinal motility medications (postoperative intravenous injection of scopolamine butylbromide and metoclopramide hydrochloride) on symptomatic paralytic ileus after a spinal operation. Results: Basic demographic data were not different. In the first phase of this study, 27 patients (32.9%) with radiographic paralytic ileus and 11 patients (13.4%) with symptomatic paralytic ileus were observed. Radiographic paralytic ileus was more often noted in patients who underwent an operation in the prone position (p=0.044); whereas the occurrence of symptomatic paralytic ileus was not different between the supine and prone positioned patients (p=0.385). In the second phase, prophylactic medications were shown to be ineffective in preventing symptomatic paralytic ileus after spinal surgery [symptomatic paralytic ileus was observed in 11.1% (4/36) with prophylactic medication and 16.7% (5/30) with a placebo, p=0.513]. Conclusion: Spinal surgery in the prone position was shown to increase the likelihood of radiographic paralytic ileus occurrence, but not symptomatic paralytic ileus. Unfortunately, the prophylactic medications to prevent symptomatic paralytic ileus after spine surgery were shown to be ineffective.
- Subjects
SPINAL cord surgery complications; GASTROINTESTINAL motility; BOWEL obstructions; RADIOGRAPHY; DRUG efficacy; DISEASE prevalence; PREVENTION
- Publication
Yonsei Medical Journal, 2015, Vol 56, Issue 6, p1627
- ISSN
0513-5796
- Publication type
Article
- DOI
10.3349/ymj.2015.56.6.1627