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- Title
Evaluation of the effect of chiropractic manipulative treatment on oxidative stress in sacroiliac joint dysfunction.
- Authors
Kültür, Turgut; Çiftçi, Aydın; Okumuş, Müyesser; Doğan, Murat; Durmaz, Şenay Arıkan; Neşelioğlu, Salim; Erel, Özcan
- Abstract
Objectives: This study aims to investigate the effect of chiropractic manipulative treatment on sacroiliac joint dysfunction (SIJD) and its relationship to oxidative stress (OXS) parameters. Patients and methods: Thirty-three patients diagnosed with SIJD (20 males, 13 females; mean age 36.3±9.7 years; range, 18 to 60 years) and 30 healthy volunteers (20 males, 10 females; mean age 36.4±12.2 years; range, 20 to 57 years) were included in this cross-sectional, case-control study conducted between February 2017 and September 2017. Manipulation was applied to the patients once a week for a duration of four weeks. The patients were evaluated at pre-treatment and one month after treatment with visual analog scale, SIJD test, and total thiol, native thiol, disulphide, and ischemia-modified albumin (IMA) as OXS indicators. Results: Prior to treatment, we demonstrated that serum native thiol (µmol/L) and total thiol (µmol/L) levels in the patient group were lower compared to control subjects (p=0.03 and p=0.02, respectively). Serum IMA levels were higher in the patient group (p=0.01). There was no change in OXS parameters after manipulative treatment in the patient group. Conclusion: Manipulation is useful in SIJD. Thiol/disulphide homeostasis and serum IMA levels may be used to measure the OXS in patients with SIJD.
- Subjects
HOMEOSTASIS; SPINAL adjustment; SULFUR compounds; SACROILIAC joint diseases; OXIDATIVE stress; BODY mass index; CROSS-sectional method; CASE-control method; DATA analysis software; DESCRIPTIVE statistics
- Publication
Turkish Journal of Physical Medicine & Rehabilitation (2587-1250), 2020, Vol 66, Issue 2, p176
- ISSN
2587-1250
- Publication type
Article
- DOI
10.5606/tftrd.2020.3301