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- Title
Csirkék reovírus-fertőzései.
- Authors
Bence, Gál; Szilvia, Farkas; Krisztián, Bányai
- Abstract
Avian reoviruses (ARVs) cause serious losses to the poultry industry worldwide. The authors provide a summary about the latest scientific results and research highlights of chicken reoviruses. Avian reovirus can either cause tenosynovitis/ viral arthritis or can join the complex aetiology of a viral enteritis/malabsorption syndrome/runting-stunting syndrome in broiler breeders or in broilers. During the past decade increasing number of tenosynovitis/viral arthrits cases were reported from vaccinated poultry flocks worldwide. Although commercial reovirus vaccines were used with success in the past thirty years, the newly emerging variants of avian reoviruses may escape immunity induced by current vaccine. To prove this hypothesis researchers started to analyse several new variants. The σC protein of the virus is responsible for cell attachment and virus neutralization, therefore this protein is key for developing protective immunity in the host. Researchers began to sequence the σC protein coding gene of new virus isolates and as a result new genotypic clusters have been identified and formed. Most importantly, it was found that emerging new variants shared low genetic similarity with vaccine strains. Considering the possible link between low genetic similarity and low protection level, practitioners turned to custom autogenous vaccines. Selecting the most appropriate strain(s) from diseased cases and use in custom vaccine may lead to induce immunity more specific to the emerging variants. Varying results with custom vaccines and the continuous evolution of ARV pose challenges to current vaccination schemes and prompt the market to seek new vaccination strategies.
- Subjects
INFECTIOUS arthritis; DNA vaccines; MALABSORPTION syndromes; POULTRY industry; VIRAL proteins; REOVIRUSES; TENOSYNOVITIS
- Publication
Magyar Állatorvosok Lapja, 2021, Vol 143, Issue 2, p95
- ISSN
0025-004X
- Publication type
Article