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- Title
ST Elevasyonsuz Miyokart Enfarktüsü Geçiren Erkek Hastalarda Serbest Testosteron Düzeyi ile Koroner Arter Hastalığının Ciddiyeti Arasındaki İlişki.
- Authors
KÖPRÜLÜ, Diyar; TAŞCANOV, Mustafa Begenç
- Abstract
Background: Syntax (SYNergy between PCI with TAXUS and Cardiac Surgery) score (SS) is an angiographic scoring system for determining the severity of coronary artery disease (CAD). High SS and low testosterone levels have found to be associated with poor cardiac events in patients with CAD. In this study, we aimed to investigate the relationship between free testosterone level and SS in male patients with Non ST-Elevation Myocardial Infarction (NSTEMI). Materials and Methods: The study included 98 male patients with NSTEMI undergoing coronary angiography. Patients were divided into two groups according to the SS values: group 1 defined as patients with SS <22, while group 2 was defined as patients with SS ≥22. Two groups were compared in terms of baseline characteristics and serum free testosterone level. Results: When compared with group 1, patients in group 2 had significantly lower levels of total testosterone (32 ± 23 vs. 23 ± 17; P = 0.032) and free testosterone (10 [4 -16]) vs. 8 [4-12] P = 0.011). In correlation analysis, SS was negatively correlated with total testosterone (r = -0.480, p = 0.001) and free testosterone level (r = -0.733, p = 0.001). Multivariate logistic regression analysis demonstrated that free testosterone was an independent predictor of high SS (odds ratio: 0.906; 95% confidence interval: 0.838-0.980, P = 0.014). Conclusions: Low free testosterone level is independently associated with high SS in male patients with NSTEMI.
- Subjects
CORONARY heart disease complications; MYOCARDIAL infarction risk factors; CONFIDENCE intervals; RISK assessment; TESTOSTERONE; LOGISTIC regression analysis; SEVERITY of illness index; CORONARY angiography; ODDS ratio
- Publication
Journal of Harran University Medical Faculty / Harran Üniversitesi Tıp Fakültesi Dergisi, 2020, Vol 17, Issue 1, p82
- ISSN
1304-9623
- Publication type
Article
- DOI
10.35440/hutfd.671941